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Volume 33, Nº 2, March and April 2020

   

DOI: https://doi.org/10.36660/ijcs.20200021

EDITORIAL

Psoriatic March, Skin Inflammation and Cardiovascular Events – Two Plaques for one Syndrome

José Laerte Boechat





Traditionally, psoriasis has been regarded as a disease affecting only the skin and joints. Unfortunately, this is still the view among many doctors. In this issue, Campos et al.,1 published an interesting observational study on cardiovascular (CV) risk factors and risk measurement in patients with psoriatic arthritis, which allow us, in this editorial, to put the spotlight on some points of great interest in this area.
As the understanding of psoriasis has evolved, the perception of the disease pathophysiology changed from an organ-specific hyperkeratotic disorder of keratinocytes to an underlying dysregulation of the immune system mediated by cytokines. These concepts led to a further shift in its classification from a skin disease to a T-cell mediated disease.2

Keywords: Psoriasis; Dermatitis, Atopic; Risk Factors; Systemic Inflammatory Response Syndrome; Arthritis, Psoriatic; Inflammation; Comorbidity.