Volume 33, Nº 2, March and April 2020
DOI: 10.5935/2359-4802.20190022
CASE REPORT
Coronary Artery Disease Associated with Coronary Anomaly and Situs Inversus Totalis in Man Submitted to Angioplasty
Alexandre Fuchs
Leandro Bonecker Lora
João Renato Cardoso Mourão
Fernando César da Costa Duarte
Igor André Telles da Cunha
Claudia Regina de Oliveira Catanheda
Introduction
Dextrocardia associated with situs inversus totalis is a rare condition with an incidence of 1:10,000 in the general population. It is characterized by a complete left-to-right reversal of the abdominal organs, including the abnormal position of the heart, resulting from changes in embryological development during the gastrulation stage (third week), characterized by the establishment of the craniocaudal, dorsoventral and right-left axes in the embryo. This condition is transmitted by autosomal recessive genes, located in the long arm of chromosome 14, which affects the genetic cascade responsible for left-right differentiation. It should be noted that most affected individuals can have normal lives.
Keywords: Coronary Diseases/complications; Dextrocardia; Situs Inversus; Heart Defects, Congenital; Angioplasty, Balloon, Coronary; Stent; Thromboytic Terapy.
