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Volume 31, Nº 5, September and October 2018

   

DOI: http://www.dx.doi.org/10.5935/2359-4802.20180038

REVIEW ARTICLE

Neutrophil-Lymphocyte Ratio in Cardiovascular Disease Risk Assessment

Heitor Oliveira Santos

Luiz Fernando Moreira Izidoro





Abstract

The development of cardiovascular diseases with atherosclerotic origin is associated with a severe inflammatory process. Neutrophils and lymphocytes are cells sensitive to this type of disorder and their ratio, known as the NLR (neutrophil/lymphocyte ratio), has shown to be useful in clinical practice. The aim of this study was to assess the role of NLR in cardiovascular disease risk assessment. We carried out a literature review in the PubMed databases searching for articles published between 2001 to 2017 and found that NLR is in fact a useful marker for cardiovascular disease. Using NLR in patients at cardiovascular risk would be useful to delineate the prognosis of patients with this disease pattern.

Keywords: Cardiovascular Diseases / physiopathology; Biomarkers; Neutrophils; Leukocyte Count; Atherosclerosis / physiopathology; Inflammation.












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