Volume 31, Nº 5, September and October 2018
DOI: http://www.dx.doi.org/10.5935/2359-4802.20180049
REVIEW ARTICLE
Cardiovascular Complications of HIV
Hugo Ribeiro Zanetti
Leonardo Roever
Alexandre Gonçalves
Elmiro Santos Resende
Abstract
With the advent of the antiretroviral therapy (ART), people infected with HIV are experiencing a significant increase in life expectancy. However, as this population ages, the morbidity and mortality due to events not related to HIV infection and/or treatment become increasingly clear. Cardiovascular diseases are among the major causes of death, and, thus, understanding the factors that trigger this situation is necessary. This review article will assess how the intrinsic and extrinsic factors related to HIV, ART and the associated risk factors can aid the epidemiological transition of mortality in this population. Moreover, we will presente the studies on the epidemiology and pathogenesis of each clinical condition related to HIV-infected individuals, in addition to introducing the major markers of cardiovascular disease in this population. Finally, we will point the main issues to be addressed by health professionals for an adequate prognosis.
Keywords: Cardiovascular Diseases; HIV; Acquired Immunodeficiency Syndrome; Acute Retroviral Syndrome/therapy; Inflammation Mediators.
