Volume 114, Nº 3, March 2020
DOI: https://doi.org/10.36660/abc.20180426
ORIGINAL ARTICLE
Effects of added salt reduction on central and peripheral blood pressure
Ana Carolina Arantes
Ana Luiza Lima Sousa
Priscila Valverde de O. Vitorino
Paulo Cesar B. Veiga Jardim
Thiago de Souza Veiga Jardim
Jeeziane Marcelino Rezende
Ellen de Souza Lelis
Rafaela Bernardes Rodrigues
Antonio Coca
Weimar Kunz Sebba Barroso
Abstract
Background: Although the effects of salt intake reduction on casual blood pressure have been extensively studied inhypertensive individuals, data on reductions of added salt on arterial stiffness in both normotensive and prehypertensivesubjects are scarce.
Objective: To evaluate the effects of progressive reduction in added salt intake (from 6 grams to 4 grams per day) onperipheral and central blood pressure and arterial stiffness in normotensive, prehypertensive and hypertensive individuals.
Methods: This was a single-blinded clinical trial with 13 weeks of follow-up. Normotensive (≤ 130/85 mmHg), prehypertensive(≥ 130 e < 139/≥ 85 e < 90 mmHg) and stage 1 hypertensive individuals (< 139/≥ 85 and < 90 mmHg) were assessed.Casual blood pressure measurements and ambulatory blood pressure monitoring were performed using the automated OMRON 705CP device, and central blood pressure was measured using the Sphygmocor®. Twenty-four-hour urinary sodium excretionand the amounts of added salt consumed were measured. Statistically significance level was set at p < 0.05 for all analysis.
Results: A total of 55 participants (18 normotensive, 15 prehypertensive and 22 hypertensive), median age 48 years (IQR:39‑54)were studied. The groups were not different in age or sex. No difference was observed in blood pressure or sodium excretionlevels before and after the intervention. No significant changes in arterial stiffness parameters were observed.
Conclusion: The progressive reduction in added salt intake during a period of 13 weeks did not cause significantreductions in peripheral and central blood pressure. (Arq Bras Cardiol. 2020; 114(3):554-561)
Keywords: Cardiovascular Diseases; Arterial Pressure; Prehypertension; Hypertension; Sodium Chloride; Diet,Sodium‑Restricted; Health Policies
