IJCS | Volume 32, Nº2, May/June 2019

263 patients Variables (n = 226) n % Sex Male 144 63.7 Female 82 36.3 Age* 59.2 ± 11.5 Alcohol 70 30.9 Smoking 78 34.5 SAH† Yes 135 59.7 No 91 40.3 DM‡ Yes 50 22.1 No 176 77.9 Dyslipidemia Yes 80 35.4 No 146 64.6 Family History Yes 95 42.0 No 131 58.0 STEMI§ 102 45.3 NSTEMI || 123 54.7 *Mean ± standard deviation; †Systemic arterial hypertension; ‡Diabetes mellitus; §ST-segment elevation myocardial infarction; || Non-ST segment elevation myocardial infarction. Source: Author’s elaboration, 2017. Albuquerque et al. Association smoking and alcohol consumption AMI Int J Cardiovasc Sci. 2019;32(3)261-268 Original Article The mean age of the patients included in the sample was 59.2 ± 11.5 years, 63.7% male. Of the patients, 59.7% had SAH, 22.1%hadDM, 35.4%were dyslipidemic, 42.0% had a family history of cardiovascular disease and 45.3% presented with STEMI (Table 1). With respect to the association between clinical characteristics and alcohol consumption, there was a difference in the distribution by gender: data showed that 59.7% of men and 85.4% of women had no alcohol drinking habit (p < 0.001). There was a significantly higher prevalence of patients without hypertension who consumed alcohol (40.7%) than alcoholic hypertensive patients (24.4%) (p = 0.010). Similarly, there was a higher prevalence of patients without diabetes (36.4%) than diabetic ones (12.0%) (p = 0.001). The other associations did not show any statistical significance (Table 2). There was a significantly lower prevalence of patients with diabetes who smoked (22.0%) than those without diabetes who smoked (38.1%) (p = 0.035). The other associations did not show any statistical significance (Table 3). None of the associations of alcohol consumption and smoking with coronary perfusion after PCI – assessed by the TIMI frame count method – and the severity of the AMI and the complexity of coronary injuries, measured respectively through the LVEF and the SYNTAX score, showed statistical significance (Tables 4 and 5). A negative and weak correlation was found between the number of pack-year and cigarettes per day with coronary perfusion after PCI – assessed using the TIMI frame count method (r = -0.174 and p = 0.041 and r = -0.192 and p = 0.027, respectively). The other correlations did not show any statistical significance (Tables 6 and 7). Discussion This is an unprecedented study, which used data from the Catarina Heart Study – a cohort study that has assessed patients admitted to the emergency department of public hospitals in Santa Catarina after a first episode of AMI – and found a negative correlation between variables related to smoking and the TIMI frame count (TFC), that is, to coronary perfusion after PCI. In relation to the demographic and clinical characteristics, there was a prevalence of male patients with mean age of 59.97 years, similar to the profile of patients seen in other Brazilian hospitals. 11,12 More than half of the patients claimed to suffer from SAH, whereas only 22.1% of patients had DM and 35.4% had dyslipidemia. Similar data were found by Soares et al., 13 who showed that the majority of patients had hypertension (60.3%), but only 24% and 35% had diabetes and dyslipidemia, respectively. 13 In the current study, less than half of the sample had a family history of cardiovascular disease (42%), superior to Brazilian literature data, in which prevalence ranges from 26.8 to 35%. 14,15 The results of this study demonstrated no significant difference between the mean SYNTAX score, LVEF and TFC, comparing alcoholic patients with non-alcoholic