ABC | Volume 115, Nº2, August 2020

Original Article Almeida Junior et al. Takotsubo Multicenter Registry (REMUTA) Arq Bras Cardiol. 2020; 115(2):207-216 Figure 3 – In-hospital complications. PCR: APE acute pulmonary edema; CRA: cardiorespiratory arrest; IMV: invasive mechanical ventilation; NIMV: non-invasive mechanical ventilation. Figure 4 – Overall 1-year survival. mortality (4.1% versus 35% – 50%). In the literature, there is a scarcity of data on secondary TTS, for instance, even simple data on the incidence of this subgroup in registries. A recently published systematic review, involving 54 observational studies with a total of 4,679 patients with TTS evaluating long-term prognosis showed an in-hospital mortality of 2.4%. The yearly rate of mortality during follow-up (median of 28 months with interquartile range of 23 – 34) was 3.5%. Multivariate analysis identified the following 3 predictors of mortality: more advanced age, atypical form of ventricular ballooning, and physical stress. This corroborates our findings, namely, that this is not a 212