ABC | Volume 115, Nº2, August 2020

Review Article Trombetta et al. BDNF in cardiovascular protection and exercise Arq Bras Cardiol. 2020; 115(2):263-269 33. Nakahashi T, Fujimura H, Altar CA, Li J, Kambayashi J, Tandon NN, et al. Vascular endothelial cells synthesize and secrete brain-derived neurotrophic factor. FEBS Lett. 2000;470(2):113-7. 34. Shen T , You Y , Joseph C, Mirzaei M, Klistorner A, Graham SL, Gupta V . BDNF polymorphism: a review of its diagnostic and clinical relevance in neurodegenerative disorders. Aging Dis. 2018; 9(3):523-536. 35. Miyajima F, Ollier W, Mayes A, Jackson A, Thacker N, et al. Brain derived neurotrophic factor polymorphism Val66Met influences cognitive abilities in the elderly. Genes Brain Behav. 2008;7(4):411–7. 36. de Toledo Ferraz Alves TC, Ferreira LK, Busatto GF. Vascular diseases and old age mental disorders: an update of neuroimaging findings. Curr Opin Psychiatry. 2010;23(6):491-7. 37. Alagiakrishnan K, MahD , Dyck JR, Senthilselvan A, Ezekowitz J. Comparison of two commonly used clinical cognitive screening tests to diagnose mild cognitive impairment in heart failure with the golden standard European Consortium Criteria. Int J Cardiol. 2017;228:558-62. 38. Jefferson AL. Cardiac output as a potential risk factor for abnormal brain aging. J Alzheimers Dis. 2010;20(3):813-21. 39. de la Torre JC. Cardiovascular risk factors promote brain hypoperfusion leading to cognitive decline and dementia. Cardiovasc Psychiatry Neurol. 2012;2012:367516. 40. Kaess BM, Preis SR, Lieb W, Beiser AS, Yang Q, Chen TC, et al. Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community. J Am Heart Assoc. 2015;4(3):e001544. 41. Deindl E. Mechanistic insights into the functional role of vascular endothelial growth factor and its signalling partner brain-derived neurotrophic factor in angiogenic tube formation. Acta Physiol (Oxf). 2014;211(2):268-70. 42. DeSouza CA, Shapiro LF, Clevenger CM, Dinenno FA, Monahan KD, Tanaka H, et al. Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men. Circulation. 2000;102(12):1351-7. 43. KimH, Li Q, Hempstead BL, Madri JA. Paracrine and autocrine functions of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in brain-derived endothelial cells. J Biol Chem. 2004;279(32):33538–46. 44. Nakamura K, Martin KC, Jackson JK, Beppu K, Woo CW, Thiele CJ. Brain-derived neurotrophic factor activation of TrkB induces vascular endothelial growth factor expression via hypoxia-inducible factor-1alpha in neuroblastoma cells. Cancer Res. 2006;66(8):4249–55. 45. Donovan MJ, Lin MI, Wiegn P , Ringstedt T , Kraemer R, Hahn R, Wang S, Ibañez CF , Rafii S, Hempstead BL. Brain derived neurotrophic factor is an endothelial cell survival factor required for intramyocardial vessel stabilization. Development. 2000;127(21):4531-40. 46. Lin CY, Hung SY, ChenHT, TsouHK, Fong YC,Wang SW, et al. Brain-derived neurotrophic factor increases vascular endothelial growth factor expression and enhances angiogenesis in human chondrosarcoma cells. Biochem Pharmacol. 2014;91(4):522-33. 47. Wang S, Bray P, McCaffrey T, March K, Hempstead BL, Kraemer R. p75NTR mediates neurotrophin-induced apoptosis of vascular smoothmuscle cells. Am J Pathol. 2000;157(4):1247-58. 48. Teng HK, Teng KK, Lee R, Wright S, Tevar S, Almeida RD, et al. ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. J Neurosci. 2005;25(22):5455-63. 49. Okada S, Yokoyama M, Toko H, Tateno K, Moriya J, Shimizu I, et al. Brain- derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway. Arterioscler Thromb Vasc Biol. 2012;32(8):1902–9. 50. Aberg MA, Pedersen NL, Toren K, Svartengren M, Backstrand B, Johnsson T, et al. Cardiovascular fitness is associated with cognition in young adulthood. Proc Natl Acad Sci U S A. 2009:106(49): 20906–11. 51. Erickson KI, Voss MW, Prakash RS, Basak C, Szabo A, Chaddock L, et al. Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci U S A. 2011:108(7):3017–22. 52. Chang YK, Labban JD, Gapin JI, & Etnier JL. The effects of acute exercise on cognitive performance: a meta-analysis. Brain Res. 2012;1453(250):87–101. 53. Babaei P, Azali AK, Soltani TB, &Damirchi A, Effect of sixweeks of endurance exerciseand followingdetrainingonserumbrainderivedneurotrophic factor andmemory performance inmiddle agedmales withmetabolic syndrome. J. Sports Med. Phys. Fitness. 2013;53(4):437-43. 54. Best, JR Nagamatsu LS, & Liu-Ambrose T. Improvements to executive function during exercise training predict maintenance of physical activity over the following year. Front. Hum. Neurosci. 2014;8:353. 55. Dupuy O, Gauthier CJ, Fraser SA, Desjardins-Crèpeau L, Desjardins M, Mekary S, et al. Higher levels of cardiovascular fitness are associated with better executive function and prefrontal oxygenation in younger and older women. Front. Hum. Neurosci. 2015;9:66. 56. Kramer AF , Colcombe S. Fitness effects on the cognitive function of older adults: a meta-analytic study-revisited. Perspect Psychol Sci. 2018;13(2):213-7. 57. Voss, M. W., Heo, S., Prakash, R. S., Erickson, K. I., Alves, H., Chaddock, L., et al. The influence of aerobic fitness on cerebral white matter integrity and cognitive function in older adults: results of a one-year exercise intervention. Hum. Brain Mapp. 2013;34(11), 2972–2985. doi: 10.1002/hbm.22119 58. Gregory SM, Parker B, Thompson PD. Physical activity, cognitive function, and brain health: what is the role of exercise training in the prevention of dementia?. Brain Sci. 2012;2(4):684–708. Published 2012 Nov 29. doi:10.3390/brainsci2040684 59. Duzel E, van Praag H, Sendtner M. Can physical exercise in old age improve memory and hippocampal function?. Brain. 2016;139(Pt 3):662–673. doi:10.1093/brain/awv407 60. Neeper SA, Gómez-Pinilla F , Choi J, Cotman CW . Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain Res. 1996;726(1-2):49–56. 61. Huang T, Larsen KT , Ried-LarsenM, Møller NC, Andersen LB. The effects of physicalactivity and exerciseonbrain-derived neurotrophic factor inhealthy humans: A review. Scand J Med Sci Sports. 2014;24(1):1-10. 62. Sohrabji F, Lewis DK. Estrogen-BDNF interactions: implications for neurodegenerative diseases. Front Neuroendocrinol. 2006;27(4):404–14. 63. Stimpson NJ, Davison G, Javadi AH. Joggin’ the noggin: towards a physiological understanding of exercise-induced cognitive benefits. Neurosci Biobehav Rev. 2018;88:177-86. 64. Griffin ÉW , Mullally S, Foley C, Warmington SA, O’Mara SM, Kelly AM. Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males. Physiol Behav. 2011;104(5):934-41. 65. RuscheweyhR, WillemerC, KrügerK, DuningT , WarneckeT , Sommer J ,etal. Physical activity and memory functions: an interventional study. Neurobiol Aging. 2011;32(7):1304-19. 66. Szuhany KL, Bugatti M, Otto MW. A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor. J Psychiatr Res. 2015;60:56– 64. doi:10.1016/j.jpsychires.2014.10.003 67. Zembron-Lacny A, Dziubek W, Rynkiewicz M, Morawin B, Wo ź niewski M. Peripheralbrain-derivedneurotrophicfactorisrelatedtocardiovascularriskfactors inactiveand inactiveelderlymen, BrazJMedBiolRes.2016;49(7):e5253. 268

RkJQdWJsaXNoZXIy MjM4Mjg=