ABC | Volume 115, Nº2, August 2020

Original Article Gatti et al. Custodiol®-HTK solution & prolonged cross-clamp time Arq Bras Cardiol. 2020; 115(2):241-250 Figure 1B – HTK vs. MCB cohort. PS-matched pairs. Differences on changes of blood levels of creatinine, sodium, potassium and calcium between the values early before surgery and the values immediately following patient admission to intensive care unit. HTK: histidine-tryptophan-ketoglutarate; MCB: multidose cold blood; PS: propensity score. HTK-cohort MCB-cohort Creatinine Sodium Potassium Calcium p=0.023 20 15 5 10 –10 –5 –15 0 p=0.997 p=0.299 p=0.779 Figure 2 – HTK vs. MCB cohort. PS-matched pairs. Differences on peak serum levels after surgery of CK-MB, CK-MB/CK, cTnI andAST.AST: aspartate aminotransferase; CK: creatine kinase; CK-MB: creatine kinase-MB; cTnI: cardiac troponin I; HTK: histidine-tryptophan-ketoglutarate; MCB: multidose cold blood; PS: propensity score. HTK-cohort MCB-cohort CK-MB (U/I) CK-MB/CK (%) p=0.589 20 30 40 50 60 70 80 10 0 p=0.210 p=0.122 p=0.899 cTnI (µg/l) AST (U/l) 248