ABC | Volume 114, Nº4, April 2020

Original Article Souza et al. NT-proBNP in acute coronary syndromes Arq Bras Cardiol. 2020; 114(4):666-672 1. HallC.Nt-probnp:themechanismbehindthemarker. JCardFail.2005;11(5 suppl):S81-3. 2. Januzzi JL Jr, Camargo CA, Anwaruddin S, Baggish AL, Chen AA, Krauser DG, et al. The n-terminal pro-bnp investigation of dyspnea in the emergency department (pride) study. Am J Cardiol. 2005;95(8):948-54. 3. Granger CB, Goldberg RJ, Dabbous O, Pieper KS, Eagle KA, Cannon CP, et al. Predictors of hospital mortality in the global registry of acute coronary events. Arch Intern Med. 2003;163(19):2345-53. 4. MorrowDA, Antman EM, Charlesworth A, Cairns R, Murphy SA, de Lemos JA, et al. TIMI risk score for st-elevationmyocardial infarction: a convenient, bedside,clinicalscore forriskassessmentatpresentation:an intravenousnpa for treatment of infarcting myocardium early ii trial substudy. Circulation. 2000;102(17):2031-7. 5. Killip T 3rd, Kimball JT. Treatment of myocardial infarction in a coronary care unit.Atwoyearexperiencewith250patients.AmJCardiol.1967;20(4):457-4. 6. Zeng X, Li L, Su Q. The prognostic value of n-terminal pro-brain natriuretic peptide in non-st elevation acute coronary syndromes: ameta-analysis. Clin Chem Lab Med. 2012;50(4):731-9. 7. Meune C, Drexler B, Haaf P, Reichlin T, Reiter M, Meissner J, et al. The grace score’s performance in predicting in-hospital and 1-year outcome in the era of high-sensitivity cardiac troponin assays and b-type natriuretic peptide. Heart. 2011;97(18):1479-83. 8. TimoteoAT, Toste A, Ramos R, Miranda F, FerreiraML, Oliveira JA, et al.Does admission nt-probnp increase the prognostic accuracy of grace risk score in the prediction of short-term mortality after acute coronary syndromes? Acute Card Care. 2009;11(4):236-42. 9. Guidez T, Marechaux S, Pincon C, Lamour H, Barrailler S, Decourcelle V, et al. Addition of b-type natriuretic peptide to the grace score to predict outcome in acute coronary syndrome: A retrospective (development) and prospective (validation) cohort-based study. Emerg Med J. 2012;29(4):274-9. 10. Goncalves PA, Ferreira J, Aguiar C, Seabra-Gomes R. TIMI, PURSUIT, and GRACE risk scores: sustained prognostic value and interaction with revascularization in NSTE-ACS. Eur Heart J. 2005;26(9):865-72. 11. Yan AT, Yan RT, Tan M, Casanova A, Labinaz M, Sridhar K, et al. Risk scores for risk stratification in acute coronary syndromes: useful but simpler is not necessarily better. Eur Heart J. 2007;28(9):1072-8. 12. Correia LC, Freitas R, Bittencourt AP, Souza AC, Almeida MC, Leal J, et al. Prognostic value of grace scores versus timi score in acute coronary syndromes. Arq Bras Cardiol. 2010;94(5):613-9. 13. Apple FS, Quist HE, Doyle PJ, Otto AP, Murakami MM. Plasma 99th percentile reference limits for cardiac troponin and creatine kinasembmass forusewithEuropeanSocietyofCardiology/AmericanCollegeOfCardiology consensus recommendations. Clin Chem. 2003;49(8):1331-6. 14. Hanley JA, McNeil BJ. A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology. 1983;148(3):839-43. 15. Xanthakis V, Sullivan LM, Vasan RS, Benjamin EJ, Massaro JM, D’Agostino RB, et al. Assessing the incremental predictive performance of novel biomarkers over standard predictors. Stat Med. 2014;33(15):2577-84. 16. Peduzzi P, Concato J, Kemper E, Holford TR, Feinstein AR. A simulation study of the number of events per variable in logistic regression analysis. J Clin Epidemiol. 1996;49(12):1373-9. 17. Yeboah J, McClelland RL, Polonsky TS, Burke GL, Sibley CT, O’Leary D, et al. Comparison of novel riskmarkers for improvement in cardiovascular risk assessment in intermediate-risk individuals. JAMA. 2012;308(8):788-95. 18. Almeida R, Mariano L, Gavina C, Pinho T, Vasconcelos M, Ferreira A, et al. The value of nt-probnp in early risk stratification of acute coronary syndromes. Rev Port Cardiol. 2006;25(1):71-5. 19. Bassan F, Bassan R, Esporcatte R, Santos B, Tura B. Very long-termprognostic role of admission bnp in non-st segment elevation acute coronary syndrome. Arq Bras Cardiol. 2016;106(3):218-25. 20. Galvani M, Ottani F, Oltrona L, Ardissino D, Gensini GF, Maggioni AP, et al. N-terminal pro-brain natriuretic peptide on admission has prognostic value across the whole spectrumof acute coronary syndromes. Circulation. 2004;110(2):128-34. 21. Ranjith N, Pegoraro RJ, Naidoo DP, Esterhuizen TM. Prognostic value of n-terminal-pro-brain natriuretic peptide measurements in patients with acute coronary syndromes. Cardiovasc J S Afr. 2006;17(2):60-6. 22. Vieira C, Nabais S, Ramos V, Braga C, Gaspar A, Azevedo P, et al. Multimarker approach with cystatin c, n-terminal pro-brain natriuretic peptide, c-reactive protein and red blood cell distribution width in risk stratification of patients with acute coronary syndromes. Rev Port Cardiol. 2014;33(3):127-36. References Ethics approval and consent to participate This study was approved by the Ethics Committee of the Monte Tabor under the protocol number 36/11. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study. 671