IJCS | Volume 32, Nº1, January/ February 2019

37 Table 1 - Distribution of cases without coronary artery disease, with mild obstructive coronary disease (< 50%), with severe obstructive coronary disease (< 50%), and that did not undergo catheterization relative to the presence or not of periodontal disease or edentulous condition No periodontal disease [50] Periodontal disease [113] Edentulous [182] Deaths / total No coronary disease 16 19 31 11 / 66 (16.7%) At least one coronary obstruction, always < 50% 3 5 4 2 / 12 (16.7%) At least one coronary obstruction, ≥ 50% 28 80 125 58 / 233 (24.9%) No catheterization 3 9 22 12 / 34 (35.3%) Deaths / total 2/50 (4.0%) 17 / 113 (15.0%) 64 / 182 (35.2%) 83 / 345 (24.0%) Chart 1 - Group A, formed by edentulous patients with at least one coronary obstruction ≥ 50%, compared with Group B, formed by patients with no periodontal disease and no coronary disease. Moras et al. Impact of periodontal disease and coronary disease Int J Cardiovasc Sci. 2019;32(1)35-40 Original Article with active periodontal disease and at least one coronary obstruction, ≥ 50% (Group C), with 80 elements. During the time interval, the number of deaths in Group A was 43, while in Group C, only 14 deaths occurred. The Hazard Ratio Group A vs Group C was equal to 2.512 (95%CI: 1.491-4.234). The p-value foundwhen comparing the curves was 0.0017. Finally, it was possible to create Chart 3, by comparing Group A, with 125 elements, with the group of patients with no periodontal disease and at least one coronary obstruction ≥ 50% (Group D), with 28 elements. Within the 10-year-follow-up, 43 deaths occurred inGroupAand only 1 death in Group D. In this comparison, the p value was 0.004 and the hazard ratio was 10.496 (4.988-22.089). Discussion This study, whose objective was to understand the relation, in terms of the morbimortality, between periodontal disease (PD) and acute coronary syndrome