IJCS | Volume 31, Nº6, November / December 2018

639 Figure 6 - Reproducibility analysis for repeated measurements of RV free wall longitudinal (two-dimensional) strain and RVGS: RV global longitudinal (two-dimensional) strain (Bland-Altman). (a) RVFWS intraobserver variability; (b) RVGS intraobserver variability; (c) RVFWS interobserver variability; (d) RVGS interobserver variability. Table 4 - Reproducibility analysis for retest measurements of RVFWS and RVGS Reproducibility analysis ICC CI(95%) RVFWS intra-observer 0.975 0.932 - 0.991 RVFWS inter-observer 0.977 0.927 - 0.992 RVGS intra-observer 0.983 0.952 - 0.994 RVGS inter-observer 0.966 0.894 - 0.989 RVFWS: right ventricular (RV) free wall longitudinal 2Dstrain; RVGS: RV global longitudinal 2Dstrain; ICC: intra-class correlation coefficient; CI: confidence interval. Felix et al. RV function by 2D strain in left-sided valve disease Int J Cardiovasc Sci. 2018;31(6)630-642 Original Article primary involvement of the myocardium, due to the inflammatory and fibrotic processes inherent to this disease. Using 2DS, Pirat et al., 28 and Ikeda et al., 29 demonstrated the occurrence of alterations in RV systolic function in patients with pulmonary artery hypertension, proportional to the severity of the disease, which could help explain some of our findings. We compared the parameters of RV systolic function with RVEF 3D, and found a moderate, negative correlation between RVEF 3D and RVGS, RVEF 3D and RVFWS, and a moderate positive correlation between RFVE 3D and FAC, with weaker correlations for TAPSE and PSV. These findings are in accordance with previous studies, showing good correlation between RV 2DS parameters and RVEFmeasured by CMR 30 and FACwith RVEF measured by CMR. 31 When the populationwas divided into two categories, according to the absence of RV dysfunction (group A, RVEF ≥ 44% by 3DE) and the presence of RV dysfunction (group B, RVEF < 44% by 3DE) we found a significant