IJCS | Volume 31, Nº2, Março / Abril 2018

189 73. Meira WS, de Castro AM, Gontijo ED, Rassi A, Luquetti AO, Machado- Coelhos GL, et al. [Evaluation of blood tests, complement-mediated lysis and polymerase chain reaction in the verification of therapeutic efficacy in Chagas disease]. Rev Soc Bras Med Trop. 2006;39 Suppl 3:107-9. PMID: 17605216. 74. Rassi A Jr, Rassi A, Rassi SG. Predictors of mortality in chronic Chagas disease: a systematic review of observational studies. Circulation. 2007;115(9):1101-8. doi: 10.1161/CIRCULATIONAHA.106.627265. 75. Rassi A Jr, Rassi A, Little WC, Xavier SS, Rassi SG, Rassi AG, et al. Development and validation of a risk score for predicting death in Chagas' heart disease. N Engl J Med. 2006;355(8):799-808. doi: 10.1056/ NEJMoa053241. 76. Morillo CA, Marin-Neto JA, AvezumA, Sosa-Estani S, Rassi A Jr, Rosas F, et al; BENEFIT Investigators. Randomized trial of benzonidazole for chronic Chagas’ cardiomyopathy. N Engl J Med. 2015;373(14):1295-306. doi: 10.1056/NEJMoa1507574. 77. Rassi A Jr, Marin JA Neto, Rassi A. Chronic Chagas cardiomyopathy: a review of the main pathogenic mechanisms and the efficacy of aetiological treatment following the BENznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT) trial. Mem Inst Oswaldo Cruz. 2017;112(3):224-35. doi: 10.1590 /0074-02760160334. 78. Bocchi EA, Marcondes-Braga FG, Bacal F, Ferraz AS, Albuquerque D, Rodrigues Dde A, et al. Atualização da diretriz brasileira de insuficiência cardíaca crônica. Arq Bras Cardiol. 2012;98(1 Suppl 1):1-33. doi: http:// dx.doi.org/10.1590/50066-782X2012000700001. 79. Issa VS, Amaral AF, Cruz FD, Ferreira SM, Guimaraes GV, Chizzola PR, et al. Beta-blocker therapy and mortality of patients with Chagas cardiomyopathy: a subanalysis of the REMADHE prospective trial. Circ HeartFail.2010;3(1):82-8.doi:10.1161/CIRCHEARTFAILURE.109.882035. 80. Bocchi EA, Bellotti G, Mocelin AO, Uip D, Bacal F, Higuchi ML, et al. Heart transplantation for chronic Chagas' heart disease. Ann Thorac Surg. 1996;61(6):1727-33. doi: 10.1016/0003-4975(96)00141-5. 81. Bocchi EA, Fiorelli A. The paradox of survival results after heart transplantation for cardiomyopathy caused by Trypanosoma cruzi. First Guidelines Group for Heart Transplantation of the Brazilian Society of Cardiology. Ann Thorac Surg. 2001;71(6):1833-8. PMID: 11426756. 82. Martinelli M, Rassi A Jr, Marin-Neto JA, de Paola AA, Berwanger O, Scanavacca MI, et al. CHronic use of Amiodarone aGAinSt Implantable cardioverter-defibrillator therapy for primary prevention of death in patients with Chagas cardiomyopathy Study: rationale and design of a randomized clinical trial. Am Heart J. 2013;166(6):976-82 e4. doi: 10.1016/j.ahj.2013.08.027. Este é um artigo de acesso aberto distribuído sob os termos da licença de atribuição pelo Creative Commons Simões et al. Cardiomiopatia da doença de chagas Int J Cardiovasc Sci. 2018;31(2)173-189 Artigo de Revisão