IJCS | Volume 33, Nº4, July and August 2020

384 Table 1 - Clinical and laboratory characteristics related to in-hospital mortality among patients with acute myocardial infarction by logistic regression Factors OR CI (95%) p-value Age a < 65 years 1.0 - - ≥ 65 years 3.58 1.89 - 6.77 < 0.001 Sex a Female 1.0 - - Male 1.01 0.57 - 1.80 0.970 Skin color a White 1.0 - - Brown 0.80 0.43 - 1.50 0.485 Black 0.44 0.17 - 1.15 0.094 Classification of AMI Non-STEMI 1.0 - - STEMI 1.62 0.83 - 3.18 0.160 Risk factors Systemic arterial hypertension 1.88 0.92 - 3.84 0.085 Diabetes mellitus 1.75 0.99 - 3.08 0.053 Kidney disease 1.15 0.43 - 3.07 0.787 Family history of coronary heart disease 0.27 0.14 - 0.55 < 0.001 Dyslipidemia 0.76 0.42 - 1.39 0.375 Depression 0.14 0.02 - 1.01 0.051 Smoking 0.78 0.43 - 1.39 0.400 Sedentary lifestyle 1.47 0.83 - 2.59 0.187 Laboratory measures Erythrocyte b 0.18 0.11 - 0.32 < 0.001 Hemoglobin b 0.65 0.55 - 0.76 < 0.001 Leukocytes c ≤ 10,5 1.0 - - > 10.5 5.52 2.71 - 11.3 < 0.001 CRP c ≤ 36,7 1.0 - - > 36.7 7.98 3.44 - 18.5 < 0.001 IG% c ≤ 0.3 1.0 - - > 0.3 11.7 4.88 - 27.9 < 0.001 TNT c ≤ 1.87 1.0 - - > 1.87 2.23 1.23 - 4.05 0.008 RDW SD c ≤ 43.2 1.0 - - > 43.2 4.34 2.22 - 8.48 < 0.001 RDW CV c ≤ 13.5 1.0 - - ≥ 13.5 4.22 2.16 - 8.23 < 0.001 NLR < 3.7 1.0 - - ≥ 3.7 16.0 5.67 - 45.0 < 0.001 NRBC Absence (0) 1.0 - - Presence (≥ 1) 33.9 15.8 - 72.8 < 0.001 MPV < 10,4 1.0 - - ≥ 10.4 3.32 1.46 - 7.55 0.004 a per 100 person-day of hospitalization; b Decreased risk with the increase of one unit of the laboratory marker; c Risk for values above the median; OR: Odds Ratio; CI: confidence interval; CRP: c-reactive protein; IG: immature granulocyte; TNT: troponin T; RDW SD: red cell distribution width measured as standard deviation; RDW CV: red blood cell distribution width as coefficient of variation; NLR: neutrophil to lymphocyte ratio; NRBC: nucleated red blood cell; MPV: mean platelet volume. to be used for clinical surveillance during patients’ hospitalization. In the last five decades, due to scientific advances and the advent of automated counting of peripheral blood cells in a safe and reliable way, the complete blood cell count has become an important clinical tool to detect variations in hematopoietic response to existing injury. Thus, these variables reflect not only ischemia and its hemodynamic repercussions, but also inflammatory processes (infectious or not) during hospitalization that may contribute to increased mortality of AMI patients, thereby complementing the risk stratification scores currently used in the clinical practice. In the present study, we demonstrated that the presence of NRBCs (OR 33.9, 95% CI: 15.8 - 72.8, p < 0.001), increases in MPV (OR 3.32, 95% CI: 1.46 - 7.55, p = 0.004) and NLR (OR 16.0, 95% CI: 5.67 - 45.0, p < 0.001) in peripheral blood was associated Monteiro Júnior et al. Hematological scoring system in AMI Int J Cardiovasc Sci. 2020; 33(4):380-388 Original Article

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