IJCS | Volume 33, Nº4, July and August 2020

324 Figure 1 - Electrocardiographic tracing records. A) WIS at six weeks; B) WIS at 15 weeks; C) L-NAME at six weeks; D) L-NAME at 15 weeks; E) WKY at six weeks; F) WKY at 15 weeks; G) SHR at six weeks; H) SHR at 15 weeks. WIS: Wistar; WKY: Wistar-Kyoto; L-NAME: NG-monomethyl-L-arginine methyl ester (L-NAME)-induced hypertension; SHR: spontaneously hypertensive rats. exhibited an increased cardiac output with normal total peripheral resistance. 9 The development of hypertension in SHR progressively promoted structural changes in the heart, which were associated with progressive cardiac hypertrophy. 9 Our results corroborate those reported by Anishchenko et al., 23 showing an increase in systolic and Grassi-Kassisse et al. ECG in hypertension models Int J Cardiovasc Sci. 2020; 33(4):321-328 Original Article