IJCS | Volume 33, Nº4, July and August 2020

1. Lechat P, Mas JL, Lascault G, Loron PH, Theard M, Klimczac M, et al. Prevalence of patent foramen ovale in patients with stroke. N Engl J Med. 1988;318(18):1148-52. 2. Saver JL, Mattle HP, Thaler D. Patent Foramen Ovale Closure Versus Medical Therapy for Cryptogenic Ischemic Stroke. A Topical Review. Stroke. 2018; 49(12):1541-8. 3. Pristipino C, Sievert H, D'Ascenzo F, Mas JL, Meier B, et al. European position paper on the management of patients with patent foramen ovale. General approach and left circulation thromboembolism. EuroIntervention. 2019;14(13):1389-402. 4. Messé SR, Gronseth GS, Kent DM, Kizer JR, Homma S. Practice advisory update summary: Patent foramen ovale and secondary stroke prevention. Report of the Guideline Subcommittee of the American Academy of Neurology. Neurology 2020 Apr 29 [Epub ahead of print] DOI: 10.1212/ WNL.0000000000009443 5. Pereira SPP, NunesA, Santos C, Kasner SE, Nunes JPL. The Role of Patent Foramen Ovale Closure in the Secondary Prevention of Cryptogenic Stroke: a Meta-Analysis Report. Int J Cardiovasc Sci. 2020; 33(4):307-317. DOI: 10.36660/ijcs.20190075 6. Lee PH, Song J-K, Kim JS, Heo R, Lee S, Kim D-H, et al. Cryptogenic Stroke and High-Risk Patent Foramen Ovale. The DEFENSE-PFO Trial. J Am Coll Cardiol. 2018;71(20):2335-42. 7. Mas JL, Derumeaux G, Guillon B, Massardier E, Hosseini H, Mechtouff L, et al. Patent Foramen Ovale Closure or Anticoagulation vs. Antiplatelets after Stroke. N Engl J Med. 2017;377(11):1011-21. 8. Aggeli C. Verveniotis A. Andrikopoulou E. Vavuranakis E. Toutouzas K. Tousoulis D. Echocardiographic features of PFOs and paradoxical embolism: A complicated puzzle. Int J Cardiovasc Imaging. 2018;34(12):1849-61. 9. Kutty S, Sengupta PP, Khandheria BK. Patent foramen ovale: the known and the to be known. J Am Coll Cardiol. 2012;59(19):1665-71. 10. Wahl A, Jüni P, Mono ML, Kalesan B, Praz F. Long-Term Propensity Score–Matched Comparison of Percutaneous Closure of Patent Foramen OvaleWithMedical TreatmentAfter Paradoxical Embolism. Circulation. 2012;125(6):803-12 References 320 Felix & Alcantara PFO closure in stroke, an evolving question Int J Cardiovasc Sci. 2020; 33(4):318-320 Editorial This is an open-access article distributed under the terms of the Creative Commons Attribution License

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