IJCS | Volume 33, Nº4, July and August 2020

397 inflamed tissue using a threshold of 2.7g/mL, and when using a threshold of 4.1g/mL, there was an increase in EF of 3.8% per 100cm 3 decrease. These findings showed a correlation between the reduction of the intensity and extension of 18F-FDG uptake due to myocardial inflammation in patients with CS and improvement in LVEF. Based on this small study, serial PET scanning could be useful in guiding the immunosuppressive therapy, preventing the development of heart failure in patients with CS. Table 4 summarizes the use of 18F-FDG PET in the management of CS. PET/MRI The combination of PET with MRI in a single acquisition is now possible with the use of advanced hybrid cameras. Despite the elevated price of the equipment, hybrid scanners can offer great benefit Figure 4 – A. 18F-fluorodeoxyglucose-positron emission tomography (18F-FDG PET) whole body and fused PET/CT of the heart at baseline and follow-up of a 54-year-old female presenting with second and third heart block. Diagnosed with cardiac sarcoidosis, the patient started steroids and had implantable cardioverter defibrillator implantation. Scan 1 : Whole-body: bilateral FDG-avid pulmonary patchy broncho-vascular micronodules, bilateral hilar and mediastinal FDG avid lymph nodes. Cardiac findings: normal perfusion findings but intense FDG uptake in the septum. Follow-up of seven months afterwards ( Scan 2 ): Whole body: resolution of the uptake seen previously. Cardiac findings: normal perfusion and no FDG uptake. B. Baseline study with rubidium-82 (top line) and 18F-FDG (bottom line) in short axis, horizontal long axis and vertical long axis, showing a normal perfusion scan with intense FDG uptake in the septum Wiefels et al. 18F-FDG PET/CT and cardiac sarcoidosis Int J Cardiovasc Sci. 2020; 33(4):389-400 Review Article