IJCS | Volume 33, Nº3, May / June 2020

221 Table 3 - Spearman correlation between e cardiovascular event risk determined by the Framingham risk score and the studied variables Correlation coefficient p-value* Body mass index -0.025 0.753 Waist circumference 0.088 0.261 Duration of known hypertension (in years) 0.003 0.967 Number of used medications 0.158 0.042 Glomerular filtration rate (GFR) -0.204 0.008 Serum urea 0.222 0.004 Serum albumin 0.053 0.500 Serum glucose 0.198 0.010 Serum total cholesterol 0.189 0.015 Serum triglycerides 0.170 0.029 Serum uric acid 0.234 0.002 24h urinary protein 0.074 0.342 Microalbuminuria 0.064 0.416 * Spearman Correlation. Table 4 - Stepwise multiple linear regression model with cardiovascular event risk determined by the Framingham risk score as dependent variable B Standar error β p-value 95%CI Lower Upper Sex (male) 8.73 1.25 0.46 < 0.001 6.27 11.19 Total cholesterol 0.05 0.01 0.25 < 0.001 0.02 0.08 GFR -0.11 0.04 -0.18 0.007 -0.18 -0.03 Number of medications 0.55 0.22 0.17 0.012 0.12 0.98 Note: R2 = 0.19 for model 1 with sex variable; ΔR2 = 0.05 with sex and total cholesterol as independent variables; ΔR2 = 0.04 with sex, total cholesterol and glomerular filtration rate as independent variables; ΔR2 = 0.03 with sex, total cholesterol, glomerular filtration rate and number of medications as independent variables. GFR: glomerular filtration rate. Moreira et al. Cardiovascular risk in hypertensive individuals Int J Cardiovasc Sci. 2020; 33(3):217-224 Original Article towards controlling CVR factors in the population with lower educational attainment. 18,20 Classification of the CVR is particularly important for establishing an effective and individualized care plan. In this study, the CVR of hypertensive individuals, measured by the FRS, was considered low (median of 9% in 10 years) and associated with male sex, total cholesterol, number of medications used and GFR. In a study on 50 hypertensive individuals treated in a public, multidisciplinary outpatient clinic inMinas Gerais state, Brazil, 74% had low cardiovascular risk. 17 Similar results were found in the Longitudinal Study of Adult Health (ELSA-Brazil) conducted with public employees of higher education institutions in Brazil, where 82.8% of the individuals presented low CVR. 21 In our study, CVR was higher 8.73% greater in males than females. In the study of the behavior of cardiovascular diseases, the issue of gender cannot be ignored, given the high prevalence of risk factors for these diseases that are associated with sex. In contrast, a study conducted with elderly patients in Goiânia showed that some risk factors for CVDs are more frequent in elderly women, such as dyslipidemia and sedentary lifestyle. 22 In addition, a survey conducted in São Paulo showed that women presented better blood pressure control than men; 23 such resultsmay be related to the behavior of women in relation to their health condition, not only by seeking more health services, but also because they have a greater tendency to follow the proposed treatments. 24,25 In this context, PHC actions must consider individual characteristics, which can facilitate adherence to treatment and, consequently, reduce morbidity and mortality. by the local health system, encouraging the practice of physical activity. In addition, national data show that physical inactivity increases with age, especially among individuals with lower education levels, which contributes to increased CVR in the Brazilian population. 14 In this sense, efforts should be directed