IJCS | Volume 33, Nº3, May / June 2020

1. World Health Organization. WHO. Director-General's opening remarks at the media briefing on COVID-19 - 11 March 2020. [Internet]. [Cited in 2020 March 21] [Epub ahead print]. Available from: https://www.who.int/dg/speeches/detail/ whodirector-general-s-opening-remarks-at-the-media-briefing- on-covid-19---11-march-2020 .Lancet Infect Dis. 2020 Feb 19.pii:S1473-3099(20)30120-1. 2. Dong E, Du H, Gardner L. An interactive web-based dashboard to track COVID-19 in real time. Lancet Infect Dis. 2020 Feb 19. pii: S1473-3099(20)30120-1. [Epub ahead print] [Cited in 2020 March 20]. Available from: https://www.arcgis.com/apps/opsdashboard/index. html#/bda7594740fd40299423467b48e9ecf6. 3. Wu Z, McGoogan JM. Characteristics of and Important Lessons from the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72314 Cases From the Chinese Center for Disease Control and Prevention. JAMA.2020 Feb 24. [Cited 2020 February 24]. Available from: https://jamanetwork.com/ 4. Imperial College - COVID19-Global-Impact- 26-03-2020; Walker PGT, Whittaker C, Watson O, The Global Impact of COVID-19 and Strategies for Mitigation and Suppression. WHO Collaborating Centre for Infectious Disease Modelling, MRC Centre for Global Infectious Disease Analysis, Abdul Latif Jameel Institute for Disease and Emergency Analytics, Imperial College London (2020) .[Cited in 2020 March 20]. Available from: https://www.imperial.ac.uk/media/ imperial-college/medicine/sph/ide/gida-fellowships/Imperial- College-COVID19-Global-Impact-26-03-2020.pdf 5. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020; 395(10223):497-506. 6. Onder G, Rezza G, Brusaferro S. Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy. JAMA. 2020 March 23. DOI: 10.1001/jama.2020.4683. [Epub ahead of print] 7. Li B, Yang J, Zhao F, Zhi L, Wang et al, Prevalence and impact of cardiovascularmetabolic diseases onCOVID-19 inChina. ClinRes Cardiol. 2020 Mar 11. DOI: 10.1007/s00392-020-01626-9. [Epub ahead of print] 8. Driggin E, Madhavan MV, Bikdeli B, Chuich T, Laracy J, Bondi- Zoccai G, et al. Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the Coronavirus Disease 2019 (COVID-19) Pandemic, J am Coll Cardiol. 2020 Mar 18. Pii:S0735-1097(20)34637-4 [Epub ahead of print] 9. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020 Feb 7. DOI:10.1001/ jama.2020.1585.[Epub ahead of print] 10. Lippi G, Lavie CJ, Sanchis-Gomar F. Cardiac troponin I in patients with coronavirus disease 2019 (COVID-19): Evidence from a meta- analysis. Prog Cardiovasc Dis. 2020 Mar 10. pii: S0033-0620(20)30055-4. [Epub ahead of print] 11. Zhou F, Yu T, Du R, Fan G, Liu Y, Xiang J, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020 Mar 28;395(10229):1054-62. 12. Ruan Q, Yang K, Wang W, Jiang L, Song J. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive Care Med. 2020 Mar 3. DOI: 10.1007/ s00134-020-05991-x [Epub ahead of print] 13. Xu Z, Shi L, Wang Y, Zhang J, Huang L, Zhang C, et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med. 2020 Feb 18. pii:S221-3- 2600(20)30076-X [Epub ahead of print] 14. Liu Y, Yang Y, Zhang C, Huang F, Wang F, Yuan J, et al. Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury. Sci China Life Sci. 2020; 63(3):364-74. 15. Inciardi RM; Lupi L, Zaccone G, Italia L, Raffo M, Tomasoni D, et al. Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19) JAMA Cardiol.2020 Mar 27. DOI:10.1001/ jamacardio.2020.1096 [Epub ahead of print] 16. Oudit GY, Kassiri Z, Jiang C, Liu PP, Poutanen SM, Penninger JM, et al. SARS coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS. Eur J Clin Invest. 2009; 39(7):618–25. 17. Vaduganathan M, Vardeny O, Michel T, McMurray JJV, Pfeffer MA, Salomon SD. Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19DOI: March 30, 2020, N Engl J Med.2020 March 30. [Epub ahead of prnt} 18. Zheng YY, Ma YT, Zhang JY, Xie X. COVID-19 and the cardiovascular system. Nat Rev Cardiol. 2020 Mar 5. DOI: 10.1038/s41569-020-0360-5 [Epub ahead of print] References association alters heart conduction, with QT-interval prolongation and advanced atrioventricular block. In addition, those drugs interact with antiplatelet agents, anticoagulants, statins and beta-blockers . 8,20 When approaching patients with COVID-19, cardiologists shouldbe alert tonewclinicalmanifestations, such as arrhythmias, left ventricular dysfunction and systemic embolism, which might be related to that condition, since there ismuch that is still unknowabout it. The COVID-19 pandemic came to change, in a previously unimaginable way, the dynamics and functioning of societies worldwide. The challenges are gigantic, mainly concerning the strain they represent to national health systems, which have never been submitted to such a radical stress test. However, this can also be an opportunity to reorganize and strengthen health systems, and, at the same time, to highlight the pivotal role of health professionals in our society. Policymakers should pursue the most effective way to guarantee the sustainability of health systems, while ensuring that healthcare professionals receive just reward and due recognition for their effort and dedication, often ignored in times of Peace. The world has responded to this scenario of global crisis with unprecedentedwidespread solidarity. In light of the enormous challenges that lie ahead, we must ensure that this matter remains close to heart. 201 Moraes & Pinto COVID-19: A matter close to heart Int J Cardiovasc Sci. 2020; 33(3):199-202 Editorial