IJCS | Volume 33, Nº2, March / April 2020

of subclinical target organ lesion, significantly improves the capacity to predict cardiovascular events. This concept adds to the knowledge about the AVA in guiding the diagnosis, risk stratification and treatment of hypertensive patients, allowing a personalization of therapeutic strategies and reduction of hypertension-related risk. Figure 1 – Interaction between the traditional cardiovascular continuum and the vascular aging continuum (Adapted from Mikael et al.; 6 and Dzau et al. 8 ) LVH: left ventricular hypertrophy; CHD: coronary heart disease; AMI: acute myocardial infarction; AVA: accelerated vascular aging; isolated systolic hypertension 1. Nilsson PM, Boutouyrie P, Laurent S. Vascular aging: A tale of Eva and Adam in cardiovascular risk assessment and prevention. Hypertension. 2009;54(1):3-10. 2. Sociedade Brasileira de Cardiologia. VII Diretriz Brasileira de Hipertens o. Arq Bras Cardiol. 2016; 107(3Supl.3):1-83. 3. Whelton PK, Carey RM, Aronow WS, Casey DE Jr, Collins KJ, Dennison HimmelfarbCetal.2017ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, andManagement of High Blood Pressure inAdults: Executive Summary:A Report of theAmerican College of Cardiology/AmericanHeartAssociation TaskForceonClinicalPracticeGuidelines.Hypertension.2018;71(6):1269-324. 4. Williams B, Mancia G, SpieringW, Rosei EA,Azizi M, BurnierM, et al. 2018 ESH/ESCGuidelinesforthemanagementofarterialhypertension.EurHeart J. 2018;39(33):3021-104. 5. Ben-Shlomo Y, Spears M, Boustred C, May M, Anderson SG, Benjamin EJ, et al. Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects. J Am Coll Cardiol. 2014;63(7):636-46. 6. MikaelLR,PaivaAMG,GomesMM,SousaALL,JardimPC,VitorinoPVO,et al.VascularAgingandArterialStiffness.ArqBrasCardiol.2017;109(3):253-8. 7. RomanMJ, Devereux RB, Kizer JR ,Lee E, Galloway JM,Ali T, et al. Central pressure more strongly relates to vascular disease and outcome than does brachi alpressure:theStrongHeartstudy.Hypertension. 2007;50(1):197-203. 8. Dzau VJ, Antman EM, Black HR, Hayes DL, Manson JE, Plutzky J, et al. The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part I: Pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease). Circulation. 2006;114(25):2850-70. 9. Williams B, Lacy PS, Thom SM, Cruickshank K, StantonA, Collier D, et al . for the CAFE Steering Committee and Writing Committee. Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study. Circulation. 2006;113(9):1213-25. 10. Vlachopoulos C,Aznaouridis K, Stefanadis C. Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. J Am Coll Cardiol. 2010; 55(13):1318-27. 11. BarrosoWKS, Goncalves CF, Berigó JAC, MeloMA,ArantesAC, Lelis ES, et al. Tonometric and Oscillometric Methods for Measurement of Central Blood Pressure Parameters: a Comparison in Patients with Borderline Hypertension or Stage 1 Hypertension. International J Cardiovasc Sc. 2020; 33(2):145-150. References 144 Campana Arterial stiffness Int J Cardiovasc Sci. 2020; 33(2):143-144 Editorial This is an open-access article distributed under the terms of the Creative Commons Attribution License