IJCS | Volume 33, Nº2, March / April 2020

140 size did not allow us to perform stratified analysis by medication class. Lastly, the fact that this study presents an associative nature makes it impossible to inflict causality to the observed associations. Perspectives The perception of quality of life has been established as an efficient form of predicting cardiovascular events and survival rate in hypertensive patients. 16 The results of the present study showed that some modifiable factors, such as muscle strength, body mass index, educational level and blood pressure influence the quality of life of these patients, and that has not been sufficiently investigated in the literature. Thus, in practical terms, interventions such as physical exercise and nutritional monitoring that promote previous control of these variables may positively affect the quality of life of hypertensive individuals. Additionally, it is suggested to carry out further studies to evaluate a broader sample of hypertensive patients, including individuals with other morbidities such as diabetes and dyslipidemia, and longitudinal studies evaluating quality of life, as well as its influence, for longer periods. Conclusion In conclusion, it was verified that hypertensive individuals with lower body mass index, higher educational level andmuscle strength presented a better quality of life in the physical domain, while the social aspects have a positive relationship with educational level. Women report worse quality of life in the pain domain compared to men. Author contributions Conception and design of the research: Andrade-Lima A, Germano-Soares AH, Lima-Junior D, Rodrigues SLC, Ritti-Dias RM, Farah BQ. Acquisition of data: Silva GO, Rodrigues SLC, Farah BQ. Analysis and interpretation of the data: Silva GO, Andrade-Lima A, Germano- Soares AH, Lima-Junior D, Rodrigues SLC, Ritti-Dias RM, Farah BQ. Statistical analysis: Silva GO, Andrade- Lima A, Germano-Soares AH, Ritti-Dias RM, Farah BQ. Obtaining financing: Rodrigues SLC, Ritti-Dias RM, Farah BQ. Writing of the manuscript: Silva GO, Andrade- LimaA, Germano-SoaresAH, Lima-Junior D, Rodrigues SLC, Ritti-Dias RM, Farah BQ. Critical revision of the manuscript for intellectual content: Silva GO, Andrade- LimaA, Germano-SoaresAH, Lima-Junior D, Rodrigues SLC, Ritti-Dias RM, Farah BQ. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding This study was funded by Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco (FACEPE – APQ : 1177-4. 09/14). Study Association This study is not associated with any thesis or dissertation work. Ethics approval and consent to participate This study was approved by the Ethics Committee of the Universidade de Pernambuco (CEP-UPE) under the protocol number 30806014.0.0000.5207. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study. 1. Gaui EN, Oliveira GMMd, Klein CH. Mortality by Heart Failure and Ischemic Heart Disease in Brazil from 1996 to 2011. Arq Bras Cardiol. 2014;102(6):557-65. 2. Mansur AP, Favarato D. Mortality due to cardiovascular diseases in Brazil and in the metropolitan region of Sao Paulo: a 2011 update. Arq Bras Cardiol. 2012;99(2):755-61. 3. Lewington S, Clarke R, Qizilbash N, Peto R, Collins R. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for onemillion adults in 61 prospective studies. Lancet. 2002;360(9349):1903-13. 4. Picon RV, Fuchs FD, Moreira LB, Fuchs SC. Prevalence of hypertension among elderly persons in urban Brazil: a systematic review with meta- analysis. Am J Hypertens. 2013;26(4):541-8. 5. Ye R, Liu K, Zhang Z, Gong S, Chen X. Health-related quality of life of hypertension in China: a systematic review and meta-analysis. J Cardiovasc Med (Hagerstown). 2018;19(8):430-8. References Silva et al. Factors associated with quality of life Int J Cardiovasc Sci. 2020; 33(2):133-142 Original Article

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