IJCS | Volume 33, Nº2, March / April 2020

125 Variables Frequency (%)/ mean (SD) General Good adherence Poor adherence p value (< 0.05) Mean blood pressure (mmHg) (n = 158) 107.5 (98 – 120) (n = 111) 107 (98 – 120) (n = 26) 110.9 (18.82) 0.7299 Time of diagnosis of SAH (years) (n = 178) 20 (14.75 – 30) (n = 124) 20 (14.25 – 27.75) (n = 26) 22.73 (12.19) 0.3648 Follow-up time at the outpatient clinic (years) (n = 176) 15 (8 – 20.75) (n = 122) 15 (7.75 – 25.75) (n = 26) 17.23 (12.12) 0.6630 Alcoholism (n = 215) 14.41% (n = 135) 15.5% (n = 28) 10.71% 0.4017 Current smoking (n = 215) 1.64% (n = 128) 1.56% (n = 27) 3.7% 0.7544 Previous smoking (n = 182) 35.16% (n = 128) 32.81% (n = 27) 29.62% 0.5673 * Data analysis was performed using the Kruskal-Wallis test, followed by the Dunn post-test, and the comparison between the groups was done by the Mann-Whitney test (except for the variable 'age', for which it was used the one-way ANOVA test, and the comparison between the groups was done by Student's t-test). Table 2 - Comorbidities and complications Variables Frequency (%) General Good adherence Poor adherence p value (< 0.05) Previous AMI 18.5% (n = 178) 17.74% (n = 124) 19.23% (n = 26) 0.8586 Previous stroke 21.6% (n = 180) 19.53% (n = 128) 36% (n = 25) 0.6016 DM 43.95% (n = 182) 40.62% (n = 128) 44.44% (n = 27) 0.8587 Dyslipidemia 95.6% (n = 162) 93.04% (n = 115) 100% (n = 22) 0.2052 Metabolic syndrome 57.4% (n = 162) 53.04% (n = 115) 66.6% (n = 24) 0.2249 * Data analysis was done using Fisher's test. Araújo & Aras Junior Therapeutic adherence and resistant hypertension Int J Cardiovasc Sci. 2020; 33(2):121-130 Original Article spironolactone (42.86%) [potassium sparing diuretic]. The distribution of the use of these drugs according to each group can be seen in figure 2, which shows that there was no statistical difference between the groups concerning the drugs used. Regarding the use of the thiazide diuretic + ACE/ARB + CCB combination, recommended as initial therapy for patients with RH, it was found to be used by 68.8% of individuals with good adherence and 72% of those with poor adherence, with no difference between groups (p = 0.7534). Most of the individuals in both groups used 4 or 5 medications (figure 3). However, the group that had poor therapeutic