IJCS | Volume 33, Nº1, January / February 2019

90 Table 2 - Characteristics of the studies on fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and infectious endocarditis Author Year Design study N pts Clinical setting Sensitivity Specificity Accuracy Diagnostic criteria Reference standard Van Riet et al. 2010 Prospective 25 25 NVE 12% 100% 18% Visual analysis Clinical follow-up Ozcan et al. 2013 Retrospective 72 12 PVE, 52 NVE 18% nr 18% Visual analysis Clinical follow-up Saby et al. 2013 Prospective 72 72 PVE 73% 80% 76% Visual analysis (AC and NAC) Modified Duke criteria and clinical follow-up Kouijzer et al. 2013 Prospective 72 nr 39% 93% nr Visual analysis Modified Duke criteria Rouzet et al. 2014 Retrospective 39 39 PVE 93% 71% 80% Visual (AC and NAC) and semiquantitative analysis Modified Duke criteria and clinical follow-up Ricciardi et al. 2014 Retrospective 27 27 PVE 55% 100% nr Visual (AC and NAC) and semiquantitative analysis Modified Duke criteria and clinical/ microbiological follow-up Pizzi et al. 2015 Prospective 92 92 PVE 87% 92% nr Visual (AC and NAC) and semiquantitative analysis Modified Duke criteria and clinical follow-up Jimenez- Ballvè et al. 2016 Prospective 41 39 PVE, 2 NVE 88% 79% 85% Visual (AC and NAC) Modified Duke criteria and clinical/ microbiological follow-up Granados et al. 2016 Prospective 51 29 PVE, 21 NVE 82% 96% nr Visual (AC and NAC) analysis Clinical, imaging and microbiological follow-up Fagman et al. 2016 Retrospective 30 30 PVE 75% 86% 83% Visual (AC and NAC) and semiquantitative analysis Modified Duke criteria and clinical/ microbiological follow-up Guenther et al. 2017 Retrospective 26 26 PVE 94% 29% 76% Visual and semiquantitative analysis Modified Duke criteria and clinical follow-up Salomaki et al. 2017 Prospective 23 16 PVE, 7 NVE 100% 71% 91% Visual (AC and NAC) and semiquantitative analysis Modified Duke criteria and clinical/ microbiological follow-up Kouijzer et al. 2018 Retrospective 88 88 NVE 45% 100% 87.5% Visual (AC and NAC) analysis Modified Duke criteria and clinical/ microbiological follow-up de Camargo et al. 2019 Prospective 303 188 PVE, 115 NVE 93% PVE 70% NVE 90% PVE 93% NVE 91% PVE 69% NVE Visual (AC and NAC) and semiquantitative analysis Modified Duke criteria El-Dalati et al. 2019 Retrospective 14 8 PVE, 6 NVE nr 100% nr Visual (AC and NAC) and semiquantitative analysis Histological diagnosis Albano et al. PET and SPECT in endocarditis Int J Cardiovasc Sci. 2020;33(1):87-93 Review Article