IJCS | Volume 32, Nº6, November / December 2019

572 11. Mazer CD, Whitlock RP, Fergusson DA, Belley-Cote E, Connolly K, Khanykin B, et al. Six-month outcomes after restrictive or liberal transfusion for cardiac surgery. N Engl J Med. 2018;379(13):1224-33. 12. Murphy GJ, Reeves BC, Rogers CA, Rizvi SI, Culliford L, Angelini GD. Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery. Circulation. 2007;116(22):2544-52. 13. Lumley T, Diehr P, Emerson S, Chen L. The importance of the normality assumption in large public health data sets. Annu Rev Public Health. 2002;23:151-69. 14. FagerlandMW. T-tests, non-parametric tests, and large studies – a paradox of statistical practice? BMC Med Res Methodol. 2012 Jun 14;12:78. 15. Skovlund E, Fenstad GU. Should we always choose a nonparametric test when comparing two apparently nonnormal distributions? J Clin Epidemiol. 2001;54(1):86-92. 16. Goodnough LT, Shah N. Is there "magic" hemoglobin number? Clinical decision support promoting restrictive blood transfusion practices. Am J Hematol. 2015;90(10):927-33. 17. Stevens LM, Noiseux N, Prieto I, Hardy JF. Major transfusions remain frequent despite the generalized use of tranexamic acid: an audit of 3322 patients undergoing cardiac surgery. Transfusion. 2016 Jul;56(7):1857-65. 18. Horvath KA, Acker MA, Chang H, Bagiella E, Smith PK, Iribarne A, et al. Blood transfusion and infection after cardiac surgery. Ann Thorac Surg. 2013;95(6):2194-201. 19. Dorneles CC, Bodanese LC, Guaragna JC, Macaganan FE, Coelho JC, Borges AP, et al. The impact of blood transfusion on morbidity and mortality after cardiac surgery. Rev Bras Cir Cardiovasc. 2011;26(2):222-9. 20. Patel NN, Murphy GJ. Transfusion triggers in cardiac surgery: where do we go from here? Can J Anaesth. 2018;65(8):868-72. 21. Kozek-Langenecker SA, Afshari A, Albaladejo P, Santullano CA, De Robertis E, Filipescu DC, et al. Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology. Eur J Anaesthesiol. 2013;30(6):270-382. Tagliari et al. Blood transfusion in cardiovascular surgery Int J Cardiovasc Sci. 2019;32(6):565-572 Original Article This is an open-access article distributed under the terms of the Creative Commons Attribution License