IJCS | Volume 32, Nº5, September/October 2019

494 Table 1 - Characteristics of the 53 patients included in the study Number/total and (%) Age (mean ± SD) 78.4 ± 18.11 Male sex 19/53 (35.8%) Body mass index (mean ± SD) 26.13 ± 5.22 Cardiovascular risk factors: Hypertension 47/53 (88.7%) Diabetes 14/53 (26.4%) Dyslipidemia 48/53 (71.7%) Smoking 11/53 (20.8%) Coronary artery disease 28/53 (52.2%) History of myocardial infarction 5/53 (9.41%) History of PCI 10/53 (18.9%) History of CABG surgery 6/53 (11.3%) Others comorbidities: History of stroke or TIA 7/53 (13.2%) Presence of porcelain aorta 12/53 (22.6%) PASP > 50 mmHg 13/53 (24.5%) COPD 19/53 (17.0%) Creatinine > 2 mg/dl 4/53 (6.90%) Pre-implantation symptoms: History of syncope 9/53 (17.0%) NYHA II 10/53 (18.9%) NYHA III or IV 43/53 (79.1%) Use of negative chronotropic medication: 30/53 (56.6%) Beta-blockers 25/53 (47.2%) Calcium channel blocker 1/53 (1.90%) Amiodarone 2/53 (3.80%) Digoxin 5/53 (9.40%) Etiology of valve disease: Degenerative AoS 50/53 (94.3%) Bicuspid aortic valve 3/53 (5.70%) EuroSCORE: EuroSCORE median [IQR] 10.8 [7.95 - 16.81] EuroSCORE > 15% 15/53 (28.3%) Cedenilla et al. Requirements for permanent pacemaker afterTAVI Int J Cardiovasc Sci. 2019;32(5):492-504 Original Article implantation during hospital stay were presented as mean ± standard deviation, distribution variables other than normal were presented as median ± interquartile range. Distribution of the continuous variables of patients who underwent permanent pacemaker implantation during hospital stay were compared using unpaired t test (used in normal distribution variables) or using the Mann-Whitney test (used in variables with distribution other than normal). Variables with p value < 0.05 were considered statistically significant. For the multivariate analysis, logistic regression that included the variables with P value < 0.25 in the univariate analysis was used. The selection of variables in the model was performed using the step-wise method. Survival curves and pacemaker-free survival were constructed using the Kaplan-Meier method. Comparisons between the survival curves of patients undergoing implantation of different types of prostheses, and patients with conduction disorders or patients with no conduction disorders were compared using the Log-rank test. Again, results with P value < 0.05 were considered statistically significant. Results Characteristics of the population and description of the procedure From December 2011 to June 2016, 64 patients underwent TAVI at INC. Five patients with pacemakers and6patientswithbiological aorticprosthesisdysfunction were excluded before TAVI. The mean age of the 53 patients included was 78.4 years andmost of themwere females (64.2%). Themedian of the EuroSCORE was 10.8% (Interquartile range: 7.95- 16.8%). Mean ejection fraction was 58.8%withmedian of 62.4%. Table 1 shows the baseline characteristics of the 53 patients included in the study. Table 2 describes the electrocardiographic findings of 52 of the 53 patients who underwent TAVI. The medical records of one of the 53 patients had no electrocardiogram available for analysis, but it was said that the patient was in sinus rhythm. Fourteen patients (26.4%) had atrial fibrillation and 39 were in sinus rhythm. The median PR interval of these patients was 160 ms (Interquartile range: 160-200ms). The median duration of QRS complexes was 100 ms (Interquartile range: 80-140 ms) and LBBB was in 17% of the cases (9/52).