IJCS | Volume 32, Nº5, September/October 2019

459 1. Redfors B, Dworeck C, Haraldsson I, Angerås O, Odenstedt J, Ioanes D, et al. Pre treatment with P2Y12 receptor antagonists in ST-elevation myocardial infarction: a report from the Swedish Coronary Angiography and Angioplasty Registry. Eur Heart J. 2019;40(15):1202-10. 2. Soeiro AM, Casale G, Lopes MAA, Godoy LC, Bossa AS, Biselli B, et al. Is there safety in the use of clopidogrel loading dose in patients over 75 yaears of age with acute coronary syndrome. Int J Cardiovasc Sci. 2019;32(5):449-456. 3. Ariza-Solé A, Guerrero C, Formiga F, Aboal J, Abu-Assi E, Marín F, et al. Global Geriatric Assessment and In-Hospital Bleeding Risk in Elderly Patients with Acute Coronary Syndromes: Insights from the LONGEVO- SCA Registry. Thromb Haemost. 2018;118(3):581-90. 4. Alonso Salinas GL, Sanmartin M, Pascual Izco M, Rincon LM, Martin- Acuna A, Pastor Pueyo P, et al. The Role of Frailty in Acute Coronary Syndromes in the Elderly. Gerontology. 2018;64(5):422-9. 5. Tarantini G, Ueshima D, D'Amico G, Masiero G, Musumeci G, Stone GW, et al. Efficacy and safety of potent platelet P2Y12 receptor inhibitors in elderly versus nonelderly patients with acute coronary syndrome: A systematic review and meta-analysis. Am Heart J. 2018;195:78-85. 6. Savonitto S, Ferri LA, Piatti L, Grosseto D, Piovaccari G, Morici N, et al. Comparison of Reduced-Dose Prasugrel and Standard-Dose Clopidogrel in Elderly Patients With Acute Coronary Syndromes Undergoing Early Percutaneous Revascularization. Circulation. 2018;137(23):2435-45. 7. Bellemain-Appaix A, Bégué C, Bhatt DL, Ducci K, Harrington RA, Roe M, et al. The efficacy of early versus delayed P2Y12 inhibition in percutaneous coronary intervention for ST-elevation myocardial infarction: a systematic review and meta-analysis. EuroIntervention. 2018;14(1):78-85. 8. Silvain J, Cayla G, Hulot JS, Finzi J, Kerneis M, O'Connor SA, et al. High on-thienopyridine platelet reactivity in elderly coronary patients: the SENIOR-PLATELET study. Eur Heart J. 2012;33(10):1241-9. 9. Cayla G, Cuisset T, Silvain J, Leclercq F, Manzo-Silberman S, Saint- Etienne C, et al. Platelet function monitoring to adjust antiplatelet therapy in elderly patients stented for an acute coronary syndrome (ANTARCTIC): an open-label, blinded-endpoint, randomised controlled superiority trial. Lancet. 2016;388(10055):2015-22. 10. Sibbing D, Gross L, Trenk D, Jacobshagen C, Geisler T, Hadamitzky M, et al. Age and outcomes following guided de-escalation of antiplatelet treatment in acute coronary syndrome patients undergoing percutaneous coronary intervention: results from the randomized TROPICAL-ACS trial. Eur Heart J. 2018;39(29):2749-58. References Esporcatte & Rangel Platelet and elderly Int J Cardiovasc Sci. 2019;32(5):457-459 Editorial This is an open-access article distributed under the terms of the Creative Commons Attribution License