IJCS | Volume 32, Nº4, July/August 2019

383 1. Guazzi M, Bandera F, Ozemek C, SystromD, Arena R. Cardiopulmonary exercise testing: what is its value? J AmColl Cardiol. 2017;70(13):1618-36. 2. Corrà U, Agostoni PG, Anker SD, Coats AJS, Crespo Leiro MG, de Boer RA, et al. Role of cardiopulmonary exercise testing in clinical stratification in heart failure. A position paper from the Committee on Exercise Physiology and Training of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2018;20(1):3-15. 3. Balady GJ, Arena R, Sietsema K, Myers J, Coke L, Fletcher GF, et al. Clinician's Guide to cardiopulmonary exercise testing in adults: a scientific statement from the American Heart Association. Circulation. 2010;122(2):191-225. 4. Carvalho VO, Mezzani A. Aerobic exercise training intensity in patients with chronic heart failure: principles of assessment and prescription. Eur J Cardiovasc Prev Rehabil. 2011;18(1):5-14. 5. Herdy AH, Ritt LE, Stein R, Araújo CG, Milani M, Meneghelo RS, et al. Cardiopulmonary exercise test: background, applicability and interpretation. Arq Bras Cardiol. 2016;107(5):467-81. 6. Meyer T, Lucia A, Earnest CP, KindermannW. A conceptual framework for performance diagnosis and training prescription from submaximal gas exchange parameters – theory and application. Int J Sports Med. 2005;26(Suppl 1):S38-48. 7. Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee IM, et al. American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc. 2011;43(7):1334-59. 8. Zuniga JM, Housh TJ, Camic CL, Bergstrom HC, Traylor DA, Schmidt RJ, et al. Metabolic parameters for ramp versus step incremental cycle ergometer tests. Appl Physiol Nutr Metab. 2012;37(6):1110-7. 9. Beltz NM, Gibson AL, Janot JM, Kravitz L, Mermier CM, Dalleck LC. Graded exercise testing protocols for the determination of VO2max: historical perspectives, progress, and future considerations. J Sports Med. 2016;2016:3968393. 10. Myers J, Buchanan N, Walsh D, Kraemer M, McAuley P, Hamilton- Wessler M, et al. Comparison of the ramp versus standard exercise protocols. J Am Coll Cardiol. 1991;17(6):1334-42. 11. HansenD, Dendale P, Berger J, Meeusen R. Low agreement of ventilatory threshold between trainingmodes in cardiac patients. Eur J Appl Physiol. 2007;101(5):547-54. 12. Davis JA, Whipp BJ, Lamarra N, Huntsman DJ, Frank MH, Wasserman K. Effect of ramp slope on determination of aerobic parameters from the ramp exercise test. Med Sci Sports Exerc. 1982;14(5):339-43. 13. Loat CE, Rhodes EC. Relationship between the lactate and ventilatory thresholds during prolonged exercise. Sports Med. 1993;15(2):104-15. 14. Buchfuhrer MJ, Hansen JE, Robinson TE, Sue DY, Wasserman K, Whipp BJ. Optimizing the exercise protocol for cardiopulmonary assessment. J Appl Physiol Respir Environ Exerc Physiol. 1983;55(5):1558-64. 15. KindermannW, SchrmammM, Keul J. Aerobic performance diagnostics with different experimental settings. Int. J. Sports Med. 1980;1(3):110-4. 16. Myers J, Voodi L, Umann T, Froelicher VF. A survey of exercise testing: methods, utilization, interpretation, and safety in the VAHCS. J Cardiopulm Rehabil. 2000;20(4):251-8. 17. Saibene F, Minetti AE. Biomechanical and physiological aspects of legged locomotion in humans. Eur J Appl Physiol. 2003;88(4-5):297-316. 18. Silva OB, Sobral Filho DC. A new proposal to guide velocity and inclination in the ramp protocol for the treadmill ergometer. Arq Bras Cardiol. 2003;81(1):48-53. 19. Kelsey CJ, Duffin J. Changes in ventilation in response to ramp changes in treadmill exercise load. Eur J Appl Physiol OccupPhysiol. 1992;65(5):480-4. 20. Porszasz J, Casaburi R, Somfay A, Woodhouse LJ, Whipp BJ. A treadmill ramp protocol using simultaneous changes in speed and grade. Med Sci Sports Exerc. 2003;35(9):1596-603. 21. Cai ZY, Hsu CC, Su CP, Lin CF, Lin YA, Lin CL, et al. Comparison of lower limb muscle activation during downhill, level and uphill running. Isokinet Exerc Sci. 2010;18(3):163-8. 22. Vernillo G, Giandolini M, Edwards WB, Morin JB, Samozino P, Horvais N, et al. Biomechanics and physiology of uphill and downhill running. Sports Med. 2017;47(4):615-29. 23. Wall-Scheffler CM, Chumanov E, Steudel-Numbers K, Heiderscheit B. Electromyography activity across gait and incline: the impact of muscular activity on humanmorphology. Am J Phys Anthropol. 2010;143(4):601-11. 24. Swanson SC, Caldwell GE. An integrated biomechanical analysis of high speed incline and level treadmill running. Med Sci Sports Exerc. 2000;32(6):1146-55. 25. Borg GA. Psychophysical bases of perceived exertion. Med Sci Sports Exerc. 1982;14(5):377-81. 26. Meyer T, Georg T, Becker C, KindermannW. Reliability of gas exchange measurements from two different spiroergometry systems. Int J Sports Med. 2001;22(8):593-7. 27. Svedahl K, MacIntosh BR. Anaerobic threshold: the concept andmethods of measurement. Can J Appl Physiol. 2003;28(2):299-323. 28. Roseguini BT, Narro F, Oliveira AR, Ribeiro JP. Estimation of the lactate threshold from heart rate response to submaximal exercise: the pulse deficit. Int J Sports Med. 2007;28(6):463-9. 29. Rusko H, Luhtanen P, Rahkila P, Viitasalo J, Rehunen S, Härkönen M. Muscle metabolism, blood lactate and oxygen uptake in steady state exercise at aerobic and anaerobic thresholds. Eur J Appl Physiol Occup Physiol. 1986;55(2):181-6. 30. Bland JM, Altman DG. Measuring agreement in method comparison studies. Stat Methods Med Res. 1999;8(2):135-60. 31. Støren Ø, Rønnestad BR, Sunde A, Hansen J, Ellefsen S, Helgerud J. A time-saving method to assess power output at lactate threshold in well- trained and elite cyclists. J Strength Cond Res. 2014;28(3):622-9. 32. JamnickNA, Botella J, Pyne DB, BishopDJ. Manipulating graded exercise test variables affects the validity of the lactate threshold and VO 2 peak. PLoS One. 2018;13(7):e0199794. 33. Nielsen J, Holmberg HC, Schrøder HD, Saltin B, Ortenblad N. Human skeletal muscle glycogen utilization in exhaustive exercise: role of subcellular localization and fibre type. J Physiol. 2011;589(Pt 11):2871-85. 34. Mann T, Lamberts RP, Lambert MI. Methods of prescribing relative exercise intensity: physiological and practical considerations. Sports Med. 2013;43(7):613-25. 35. Londeree BR. Effect of training on lactate/ventilatory thresholds: a meta-analysis. Med Sci Sports Exerc. 1997;29(6):837-43. 36. Gaskill SE, Ruby BC, Walker AJ, Sanchez OA, Serfass RC, Leon AS. Validity and reliability of combining three methods to determine ventilatory threshold. Med Sci Sports Exerc. 2001;33(11):1841-8. 37. Aunola S, Rusko H. Reproducibility of aerobic and anaerobic thresholds in 20-50 year oldmen. Eur J Appl Physiol Occup Physiol. 1984;53(3):260-6. 38. Hunt KJ, Anandakumaran P, Loretz JA, Saengsuwan J. A new method for self-paced peak performance testing on a treadmill. Clin Physiol Funct Imaging. 2018;38(1):108-17. References Belli et al. Speed and grade increment during cardiopulmonary Int J Cardiovasc Sci. 2019;32(4):374-383 Original Article This is an open-access article distributed under the terms of the Creative Commons Attribution License