IJCS | Volume 32, Nº4, July/August 2019

341 1. Khan H, Jaffar N, Rauramaa R, Kurl S, Savonen K, Laukkanen JA. Cardiorespiratory fitness and nonfatalcardiovascular events: A population-based follow-up study. Am Heart J. 2017 Feb;184:55-61. 2. Kodama S, Saito K, Tanaka S, Maki M, Yachi Y, Asumi M, et al. Cardiorespiratory fitness as a quantitative predictor of all-causemortality and cardiovascular events in healthy men and women: a meta-analysis. JAMA. 2009;301(19):2024-35. 3. Mandsager K, Harb S, Cremer P, Phelan D, Nissen SE, Jaber W. Association of Cardiorespiratory Fitness With Long-term Mortality Among Adults Undergoing Exercise Treadmill Testing. JAMA Netw Open. 2018;1(6):e183605. 4. Harber MP, Kaminsky LA, Arena R, Blair SN, Franklin BA, Myers J, et al. Impact of Cardiorespiratory Fitness on All-Cause and Disease-Specific Mortality: Advances Since 2009. Prog Cardiovasc Dis. 2017;60(1):11-20. 5. Kaminsky LA, Arena R, Ellingsen O, Harber MP, Myers J, Ozemek C, et al. Cardiorespiratory fitness and cardiovascular disease - The past, present, and future. Prog Cardiovasc Dis. 2019;62(2):86-93. 6. Lakka TA, Laukkanen JA, Rauramaa R, Salonen R, Lakka HM, Kaplan GA, et al. Cardiorespiratory fitness and the progression of carotid atherosclerosis in middle-agedmen. Ann InternMed. 2001;134(1):12-20. 7. Ross R, Blair SN, Arena R, Church TS, Despres JP, Franklin BA, et al. Importance of Assessing Cardiorespiratory Fitness in Clinical Practice: A Case for Fitness as a Clinical Vital Sign: A Scientific Statement From the American Heart Association. Circulation. 2016;134(24):e653-e99. 8. Araújo CGS, Herdy AH, Stein R. Medida do consumo máximo de oxigênio: valioso marcador biológico na saúde e na doença. Arq Bras Cardiol. 2013;100(4):e51-e63. 9. Laukkanen JA, Rauramaa R, Makikallio TH, Toriola AT, Kurl S. Intensity of leisure-time physical activity and cancer mortality in men. Br J Sports Med. 2011;45(2):125-9. 10. Myers J, PrakashM, Froelicher V, DoD, Partington S, Atwood JE. Exercise capacity and mortality among men referred for exercise testing. N Engl J Med. 2002;346(11):793-801. 11. Ehrman JK, Brawner CA, Al-MallahMH, QureshiWT, BlahaMJ, Keteyian SJ. Cardiorespiratory Fitness Change and Mortality Risk Among Black and White Patients: Henry Ford Exercise Testing (FIT) Project. Am J Med. 2017;130(10):1177-83. 12. Laukkanen JA, Zaccardi F, Khan H, Kurl S, Jae SY, Rauramaa R. Long- term Change in Cardiorespiratory Fitness and All-Cause Mortality: A Population-Based Follow-up Study. Mayo Clin Proc. 2016;91(9):1183-8. 13. Imboden MT, Harber MP, Whaley MH, Finch WH, Bishop DL, Fleenor BS, et al. The Association between the Change in Directly Measured Cardiorespiratory Fitness across Time and Mortality Risk. Prog Cardiovasc Dis. 2019;62(2):157-62. References Araújo et al. CLINIMEX aerobic fitness questionnaire Int J Cardiovasc Sci. 2019;32(4):331-342 Original Article Conclusions In summary, we concluded that: a) C-AFQ was successfully applied in a large sample of subjects who voluntarily underwent CPET; 2b) C-AFQ was valid to estimate aerobic fitness by four specialized physicians and could be used as a non-exercise alternative when maximal CPET is unavailable or cannot be performed; c) C-AFQ can be very useful to support the planning of individualized CPET ramp protocols; d) C-AFQ’s error of estimate of VO 2 max was clinically too high in some of the subjects, with a small trend of larger errors in the upper extremes of aerobic fitness; e) C-AFQ’s error of the estimate of VO 2 max was largely independent of age, sex, major anthropometric measurements, clinical condition, regular use of ß-blockers, type of CPET ergometer and non-aerobic physical fitness levels. Author contributions Conception and design of the research: Araujo CG, Castro CL, Franca JF, de Souza e Silva CG. Acquisition of data: Araujo CG, Castro CL, Franca JF, de Souza e Silva CG. Analysis and interpretation of the data: Araujo CG, Castro CL, Franca JF, de Souza e Silva CG. Statistical analysis: Araujo CG, de Souza e Silva CG. Obtaining financing: Araujo CG. Writing of the manuscript: Araujo CG. Critical revision of the manuscript for intellectual content: Araujo CG, Castro CL, Franca JF, de Souza e Silva CG. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding This study was partially funded by CNPq/FAPERJ. Study Association This study is not associated with any thesis or dissertation work. Ethics approval and consent to participate This study was approved by the Ethics Committee of the SUPREMA under the protocol number 218/2011. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study.