IJCS | Volume 32, Nº2, May/June 2019

DOI: 10.5935/2359-4802.20190018 269 ORIGINAL ARTICLE International Journal of Cardiovascular Sciences. 2019;32(3)269-273 Mailing Address: Bárbara de Oliveira Costa Rua Presidente Pedreira, 38, bloco: 2, apt.: 6. Postal Code: 24210-470, Ingá, Niterói, RJ - Brazil. E-mail: ba.oliveiracosta@gmail.com, barbaracosta@id.uff.br Impact of Coronary Artery Bypass Grafting on Muscle Mass Reduction on the 7 th Postoperative Day Bárbara de Oliveira Costa, 1 G abrielle Maciel, 1 A na Beatriz Huguenin, 1 G eisiane da Silva, 1 S heila Moreira da Silva Guimarães, 1 W anise Maria de Souza Cruz, 1 A lexandre Siciliano Colanfranceschi, 2 Gilson Teles Boaventura 1 Universidade Federal Fluminense (UFF), 1 Niterói, RJ - Brazil Instituto Nacional de Cardiologia (INC), 2 Rio de Janeiro, RJ - Brazil Manuscript received May 28, 2018; revised manuscript August 05, 2018; accepted September 03, 2018. Abstract Background: Ischemic heart failure is a chronic and degenerative disease with high morbidity and mortality in the world. Coronary artery bypass grafting is indicated as elective treatment and may cause a catabolic state that depletes energy reserves. Data on body composition evaluation in the postoperative period of major cardiac surgery are limited. Objective: To evaluate the influence of elective coronary artery bypass grafting on body composition on the seventh postoperative day of patients with ischemic heart failure. Methods: A cross-sectional study was carried out in which eighteen volunteers with New York Heart Association Class II and III heart failure underwent coronary artery bypass grafting. The energy and protein reserves of the participants were evaluated by anthropometry in the preoperative and on the seventh postoperative day. Paired t-Test or Mann-Whitney test was used if applicable. A significance level was considered at p value < 0.05. Results: A significant loss of muscle mass was observed through the reduction of arm muscle circumference after surgery (4.2%, p 0.007). Major surgery causes hypermetabolic state and systemic inflammatory stimulus, due to the release of hormones and cytokines that may justify the observed loss of muscle mass. Conclusion: Coronary artery bypass grafting had an impact on muscle mass reduction seven days after surgery in patients with ischemic heart failure. (Int J Cardiovasc Sci. 2019;32(3)269-273) Keywords: Heart Failure/physiopathology; Heart Failure/mortality; Coronary,Artery Bypass Grafting; Body Composition; Postoperative Period. Introduction Heart failure (HF) is a chronic and degenerative disease with high morbidity and mortality in the world. Coronary artery bypass grafting (CABG) is indicated as an elective treatment and, may cause a catabolic state that depletes energy reserves. 1 Data from the preoperative body composition assessment, using the anthropometricmethod and clinical outcomes after myocardial revascularization are limited. Therefore, we aimed to demonstrate the influence of elective CABG on body composition in the postoperative period of patients with ischemic heart failure. 2 Methods This study is part of a clinical trial that assessed the association between CABG and cardiac reverse remodeling. This cross-sectional study was approved by the Research Ethics Committee of the UniversityHospital of Universidade Federal Fluminense . It was registered in the Brazilian Registry of Clinical Trials (RBR-7376mq). Patientswith ischemicHFNewYorkHeart Association (NYHA) Class II and III, 2 of both genders, undergoing elective CABG were recruited fromNational Institute of Cardiology / RJ. The inclusion criteria were: clinical and hemodynamic stability and absence of protein or caloric