IJCS | Volume 32, Nº2, May/June 2019

246 sensitive Src-and Akt-dependent activation of eNOS. Cardiovasc Res. 2007;73(2):404-13. 7. Vinson JA, Teufel K, Wu N. Red wine, dealcoholized red wine, and especially grape juice, inhibit atherosclerosis in a hamster model. Atherosclerosis. 2001;156(1):67-72. 8. Coimbra SR, Lage SH, Brandizzi L, Yoshida V, Luz PL. The action of red wine and purple grape juice on vascular reactivity is independent of plasma lipids in hypercholesterolemic patients. Braz J Med Biol Res. 2005;38(9):1339-47. 9. Carmo MCL, Dantas MIS, Ribeiro SMR. Caracterização do mercado consumidor de sucos prontos para o consumo. Braz J Fod Technol. 2015;17(4):305-9. 10. Rizzon LA, Link M. Composição do suco de uva caseiro de diferentes cultivares. Revista Ciência Rural. 2016;36(2):689-92. 11. Pepi S, Coletta A, Crupi P, Leis M, Russo S, Sansone L, et al. Geochemical characterization of elements in Vitis vinifera cv. Negroamaro grape berries grown under different soil managements. EnvironMonit Assess. 2016;188(4):211. 12. Cetó X, Gutiérrez JM, Gutiérrez M, Céspedes F, Capdevila J, Mínguez S, et al. Determination of total polyphenol index in wines employing a voltammetric electronic tongue. Anal Chim Acta. 2012;732:172-9. 13. Dani C, Oliboni LS, Vanderlinde R, Bonatto D, Salvador M, Henriquesa JA. Phenolic content and antioxidant activities of white and purple juices manufacturedwith organically-or conventionally-produced grapes. Food Chem Toxicol. 2007;45(12):2574-80. 14. Lino FM, Sá LZ, Torres IM, Rocha ML, Dinis TC, Ghedini PC, et al. Voltammetric and spectrometric determination of antioxidantcapacity of selected wines. Electrochim Acta. 2014 May 10;128:25-31. 15. Blasco AJ, González MC, Escarpa A. Electrochemical approach for discriminating and measuring predominant flavonoids and phenolic acids using differential pulse voltammetry: towards an electrochemical index of natural antioxidants. Anal Chim Acta. 2004;511(1):71-81. 16. Kilmartin PA, Zou H, Waterhouse AL. A cyclic voltammetry method suitablefot characterizing antioxidant properties of wine and wine phenolics. J Agric Food Chem. 2001;49(4):1957-65. 17. Burin VM, Falcão DL, GonzagaI LV, Fett R, Rosier JP, Bordignon-Luiz MT. Colour, phenolic content and antioxidant activity of grape juice. Ciênc Tecnol Aliment. 2010 out-dez 2010;30(4):1027-32. 18. Luciano MN, Ribeiro TP, França-Silva MS, Nascimento RJ, Oliveira EJ, França KC, et al. Uncovering the vasorelaxant effect induced by Vale do São Francisco red wine: a role for nitric oxide. J Cardiovasc Pharmacol. 2011;57(6):696–701. 19. Brizic I, Modun D, Vukovic J, Budimir D, Katalinic V, Boban M. Differences in vasodilatory response to red wine in rat and guinea pig aorta. J Cardiovasc Pharmacol. 2009;53(2);116-20. 20. Porteri E, Rizzoni D, Ciuceis C, Boari GE, Platto C, Pilu A, et al. Vasodilator effects of red wines in subcutaneous small resistance artery of patients with essential hypertension. Am J Hypertens. 2010;23(4),373-8. 21. Kawada T. Green tea consumption and risk of cardiovascular disease or stroke. Int J Cardiol. 2016 Oct 15;221:831. 22. Hugel HM, JacksonN, May B, Zhang AL, Xue CC. Polyphenol protection and treatment of hypertension. Phytomedicine. 2016;23(2):220-31. 23. Leifert WR, Abeywardena MY. Cardioprotective actions of grape polyphenols. Nutrit Res. 2008;28(11):729-37. 24. Barona J, Aristizabal JC, Blesso CN, Volek JS, Fernandez ML. Grape polyphenols reduce blood pressure and increase flow-mediated vasodilation inmenwithmetabolic syndrome. J Nutrit. 2012;142(9):1626- 32. 25. Leblais V, Krisa S, Valls J, Courtois A, Abdelouhab S, Vila AM, et al. Relaxation induced by red wine polyphenolic compounds in rat pulmonary arteries: lack of inhibition byNO-synthase inhibitor. Fundam Clin Pharmacol. 2008;22(1):25-35. 26. Li H, Xia N, Förstermann U. Cardiovascular effects andmolecular targets of resveratrol. Nitric Oxide. 2012;26(2):102-10. Britto Junior et al. Antioxidant and vasodilatory action of grape juices Int J Cardiovasc Sci. 2019;32(3)238-246 Original Article This is an open-access article distributed under the terms of the Creative Commons Attribution License

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