IJCS | Volume 31, Nº6, November / December 2018

637 Figure 4 - Mean values of echocardiographic parameters by predominant valve lesion. P value refers to difference between all groups by multiple comparisons (ANOVA). MS: mitral stenosis, MR: mitral regurgitation, AS: aortic stenosis, AR: aortic regurgitation, PSV: peak systolic velocity of tricuspid annulus(a); TAPSE: tricuspid annular plane systolic excursion (b); FAC: fractional area change (c); RVEF 3D: right ventricular (RV) ejection fraction three-dimensional echocardiography (d); RVFWS: RV free wall longitudinal two- dimensional strain (e); RVGS: RV global longitudinal (two-dimensional) strain (f). Felix et al. RV function by 2D strain in left-sided valve disease Int J Cardiovasc Sci. 2018;31(6)630-642 Original Article patients frequently present with disease in more than one valve, and therefore, we decided to include in the present study patients with combined mitral and/ or aortic lesions, to better represent the entire clinical spectrum of the disease. Considering RVEFmeasured by 3DE as an established reference standard for evaluation of RV function, most patients in our study had normal RV function (RVEF 3D ≥ 44%), although the number of patients with RV dysfunction was significant (n = 14; 27.4%). The mean