IJCS | Volume 31, Nº6, November / December 2018

628 1. World Health Organization. (WHO). Media Centre. The top 10 causes of death. Washington;2014. 2. Brasil. Ministério da Saúde. Secretaria de Vigilância à Saúde. Plano de ações estratégicas para o enfrentamento das doenças crônicas não transmissíveis no Brasil, 2011-2022. Brasilia; 2011. 3. Mansur AP, Favarato D. Mortalidade por doenças cardiovasculares no Brasil e na regiãometropolitana de São Paulo: atualização 2011. Arq Bras Cardiol. 2012;99(2):755-61. 4. Silva AKF, Barbosa MPCR, Bernardo AFB, Vanderlei FM, Pacagnelli FL, Vanderlei LCM. Cardiac risk stratification in cardiac rehabilitation programs: a reviewof protocols. Rev Bras Cir Cardiovasc. 2014;29(2):255-6. 5. Meirelles LR, Pinto VM, Medeiros AS, Berry JRS, Magalhães CK. Efeito da Atividade Física Supervisionada após seis Meses de Reabilitação Cardíaca: experiência inicial. Rev SOCERJ. 2006;19(6):474-81. 6. Milani M, Kozuki RT, Crescêncio JC, Pada V, Santos MDB, Bertini CQ,et al. Efeito do treinamento físico aeróbico em coronariopatas submetidos a um programa de reabilitação cardiovascular. Medicina (Ribeirão Preto. Online). 2007;40(3):403-11. 7. Cameirão MS, Badia SB, Oller ED, Verschure PF. Neurorehabilitation using the virtual reality based Rehabilitation Gaming System: methodology, design, psychometrics, usability and validation. J Neuroeng Rehabil. 2010;7(48):1-14. 8. Shih CH, Shih CT, Chu CL. Assisting people with multiple disabilities actively correct abnormal standing posture with a NintendoWii balance board through controlling environmental stimulation. Res Dev Disabil. 2010;31(4):936-42. 9. Cacau LAP, Oliveira GU, Maynard LG, Araújo Filho AA, Silva Junior WM, CerqueriaNetoML,et al The use of the virtual reality as intervention References Silva et al. Virtual rehabilitation for individuals with heart disease Int J Cardiovasc Sci. 2018;31(6)619-629 Original Article levels in individuals with type 2 diabetes mellitus who exercised with Nintendo Wii ® ( Wii Fit Plus) for 30 minutes for 12 weeks. That finding results from the fact that the intervention proposed is the physical exercise practice, which increases muscle capillarization, improves mitochondrial function and, via an insulin-independent mechanism, involves the muscle glucose transporter (GLUT 4), improving insulin resistance and decreasing blood glucose levels. 42 This study evidenced similar gain potentials in certain variables for both training modalities, showing VR as a complementary and innovative tool that contributes in a motivational, interactive and functional manner. Thus, the use of technologies as an intervention can be added to cardiovascular rehabilitation programs. This study has limitations, such as its reduced sample size and intervention duration, requiring further investigation to confirm its findings. In addition, there was no nutritional guidance, which might have influenced the results regarding body composition. Conclusion Both groups showed a positive effect of conventional and VR cardiovascular rehabilitation on functional capacity and blood glucose levels, but with no difference between them. However, neither body composition nor food frequency improved after the interventions. Author contributions Conception and design of the research: Silva JPLN, Novaes LFM, Santos LCR, Galindo BP, Cavalcante MA, Araújo BCG, Pacagnell FL, Freire APCF. Acquisition of data: Silva JPLN, Novaes LFM, Santos LCR, Galindo BP, Cavalcante MA, Pacagnell FL, Freire APCF. Analysis and interpretation of the data: Silva JPLN, Novaes LFM, Santos LCR, Galindo BP, Araújo BCG, Pacagnell FL, Freire APCF. Statistical analysis: Freire APCF. Obtaining financing: Cavalcante MA. Writing of the manuscript: Silva JPLN, Novaes LFM, Santos LCR, Galindo BP, Araújo BCG, Pacagnell FL, Freire APCF. Critical revision of the manuscript for intellectual content: Silva JPLN, Novaes LFM, Santos LCR, Galindo BP, Cavalcante MA, Araújo BCG, Pacagnell FL, Freire APCF. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding This studywas funded by Universidade do Oeste Paulista . Study Association This study is not associated with any thesis or dissertation work. Ethics approval and consent to participate This study was approved by the Ethics Committee o f t he Unoe s t e unde r t he pro t oco l numbe r 6243.7816.4.0000.5515. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study.