IJCS | Volume 31, Nº6, November / December 2018

659 1. Owan TE, Hodge DO, Herges RM, Jacobsen SJ, Roger VL, RedfieldMM. Trends in prevalence and outcome of heart failurewith preserved ejection fraction. N Engl J Med. 2006;355(3):251-9. 2. Jorge AL, Rosa ML, Martins WA, Correia DM, Fernandes LC, Costa JA, et al. The prevalence of stages of heart failure in primary care: a population-based study. J Card Fail. 2016;22(2):153-7. 3. Borlaug BA, Melenovsky V, Russell SD, Kessler K, Pacak K, Becker LC, et al. Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction. Circulation. 2006;114(20):2138-47. 4. Ennezat PV, Lefetz Y, Marechaux S, Six-Carpentier M, Deklunder G, Montaigne D, et al. Left ventricular abnormal response during dynamic exercise in patients with heart failure and preserved left ventricular ejection fraction at rest. J Card Fail. 2008;14(6):475-80. 5. ShahAM, Solomon SD. Phenotypic andpathophysiological heterogeneity in heart failure with preserved ejection fraction. Eur Heart J. 2012;33(14):1716-7. 6. Samson R, Jaiswal A, Ennezat PV, Cassidy M, Le Jemtel TH. Clinical phenotypes in heart failure with preserved ejection fraction. J AmHeart Assoc. 2016;5(1). pii: e002477. 7. Pedrotty DM, Jessup M. "Frailty, thy name is woman": syndrome of women with heart failure with preserved ejection fraction. Circ Cardiovasc Qual Outcomes. 2015;8(2 Suppl 1):S48-51. References Figure 4 - Future management of heart failure with preserved ejection fraction. HFPEF: heart failure with preserved ejection fraction. Phenotyping of HFPEF subgroups Differential diagnosis of phenocopies Clinical trials with new therapeutic targets Mesquita et al. HFPEF phenotypes Int J Cardiovasc Sci. 2018;31(6)652-661 Review Article interpretation of the data: Mesquita ET, Grion DC, Kubrusly MC, Silva BBFF, Santos EAR. Writing of the manuscript: Mesquita ET, Grion DC, Kubrusly MC, Silva BBFF, Santos EAR. Critical revision of the manuscript for intellectual content: Mesquita ET, Grion DC, Kubrusly MC, Silva BBFF, Santos EAR. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This study is not associated with any thesis or dissertation work. Ethics approval and consent to participate This article does not contain any studies with human participants or animals performed by any of the authors.