IJCS | Volume 31, Nº5, September / October 2018

547 1. Osgood MJ, Hocking KM, Voskresensky IV, Voskresensky IV, Li FD, Komalavilas P, et al: Surgical vein graft preparation promotes cellular dysfunction, oxidative stress, and intimal hyperplasia in human saphenous vein. J Vasc Surg. 2014;60(1):202-11. 2. Kunadian B, Dunning J, Millner RW. Modifiable risk factors remain significant causes of medium term mortality after first time Coronary artery bypass grafting. J Cardiothorac Surg. 2007 Dec 3;2:51. 3. Goldman S, Zadine K, Krasnicka B, Moritz T, Sethi G, Copeland JG, et al. Predictors of graft patency 3 years after coronary artery bypass graft surgery. Department of Veterans Affairs Cooperative Study Group No. 297. J Am Coll Cardiol. 1997;29(7):1563-8. 4. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373-83. 5. Kitamura S. Physiological and metabolic effects of grafts in coronary artery bypass surgery. Circ J. 2011;75(4):766-72. 6. Parolari A, Poggio P, Myasoedova V, Songia P, Bonalumi G, Pilozzi A, et al. Biomarkers in coronary artery bypass surgery: ready for prime time and outcome prediction. Front Cardiovasc Med. 2016 Jan 5;2:39. 7. Campeau L. Lipid lowering and coronary bypass graft surgery. Curr Opin Cardiol. 2000;15(6):395-9. 8. Menkis AH, Carley SD, Clough TM. Reoperation after coronary bypass grafting. Can Fam Physician. 1993 Feb;39:325-32. 9. Goldman S, Zadina K, Moritz T, Ovitt T, Sethi G, Copeland JG, et al; VA Cooperative Study Group. Long-termpatency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: results from a Department of Veterans Affairs Cooperative Study. J Am Coll Cardiol. 2004;44(11):2149-56. 10. Desai ND, Naylor CD, Kiss A, Cohen EA, Feder-Elituv R, Miwa S, et al; Radial Artery Patency Study Investigators Impact of patient and target- vessel characteristics on arterial and venous bypass graft patency: insight from a randomized trial. Circulation. 2007;115(6):684-91. References Karabag et al. Comorbidity and graft patency Int J Cardiovasc Sci. 2018;31(5)544-547 Brief Communication Conclusion Graft occlusion is more common among patients with a high comorbidity burden. Our opinion is that considering comorbid conditions alongwith conventional atherosclerotic risk factors at the preoperative and postoperative periods would have a favorable impact on graft patency among patients undergoing bypass surgery. The CCI scoring system may be helpful to identify patients at increased risk at both the preoperative and postoperative periods. Author contributions Conception and design of the research: Karabag T. Acquisition of data: Karabag T, Sahin B, Coskun E, Somuncu UM, Cakir MO. Analysis and interpretation of the data: Karabag T, Somuncu UM. Writing of the manuscript: Karabag T, Kalayci B, Coskun E, Cakir MO. Critical revision of the manuscript for intellectual content: Kalayci B, Coskun E. Supervision / as the major investigador: Karabag T. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This study is not associated with any thesis or dissertation work. This is an open-access article distributed under the terms of the Creative Commons Attribution License