IJCS | Volume 31, Nº5, September / October 2018

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Accumulated exercise in infarcted old rats Int J Cardiovasc Sci. 2018;31(5)505-512 Original Article Conclusions In conclusion, data of the present study are that aerobic training, regardless the arrangement of the program - continuously or fractioned -, causes significant increase on physical capacity of elderly rats, as well as acts protecting against further impairments caused by MI injuries. However, accumulated aerobic exercise seems to be a better approach once CE showed decreased exercise capacity in comparison with the time before MI, as well an elevated index of pulmonary congestion, whereas both parameters were stable in the AE group. Author contributions Conception and design of the research: Rodrigues B. Acquisition of data: Feriani DJ. Analysis and interpretation of the data: Feriani DJ, Coelho-Júnior HJ. Statistical analysis: Feriani DJ, Coelho-Júnior HJ. Obtaining financing: Rodrigues B. Writing of the manuscript: Feriani DJ, Coelho-Júnior HJ, Rodrigues B. Critical revision of themanuscript for intellectual content: Irigoyen MC, Rodrigues B. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding This study was funded by FAPESP (2013/14788-9). Study Association This study is not associated with any thesis or dissertation work. Ethics approval and consent to participate This study was approved by the Ethics Committee on Animal Experiments of the Universidade São Judas Tadeu under the protocol number 008/2013.