IJCS | Volume 31, Nº4, July / August 2018

440 Borges et al. Oncocardiology and the symptom fatigue Int J Cardiovasc Sci. 2018;31(4)433-442 Review Article different types and stages of cancer receiving or not treatment with radiotherapy. 53 Fatigue may also be assessed with the Piper Fatigue Scale. Revised and validated in Brazil in 2009, this scale covers all dimensions of fatigue and can be applied to cancer patients at all stages of the disease. This scale establishes a cutoff point from which the individual should be regarded as fatigued. 54 Another widely used questionnaire is the Functional Assessment of Cancer Therapy-Fatigue (FACT-F), which was validated and applied in a study carried out at the Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) in 2008 and showed a negative impact of fatigue on the quality of life of patientswith breast cancer undergoing chemotherapy. 55 Conclusion Although fatigue is a common symptom in patients with cancer, it receives little attention in daily clinical practice. In recent decades, fatigue has been progressively recognized by its impact on the patients’ quality of life and survival. Fatigue is also one of the cardinal symptoms of HF. Cardiac surveillance and oncocardiology are concepts that are being incorporated by multidisciplinary teams caring for patients with cancer. Therefore, the identification of fatigue and its pathophysiological mechanisms, as well as its correct stratification and therapeutic approach, are fundamental steps to be met by healthcare professionals involved in the care of patients with cancer. Author contributions Conception and design of the research: Borges JA, Quintão MMP, Chermont SSMC, Mendonça Filho HTF, MesquitaET. Acquisitionof data: Borges JA, QuintãoMMP, Chermont SSMC, Mendonça Filho HTF, Mesquita ET. Analysis and interpretationof thedata: : Borges JA, Quintão MMP, Chermont SSMC, Mendonça Filho HTF, Mesquita ET. Statistical analysis: Borges JA.Writingof themanuscript: Borges JA, Quintão MMP, Chermont SSMC, Mendonça FilhoHTF,Mesquita ET. Critical revision of themanuscript for intellectual content: Borges JA,QuintãoMMP, Chermont SSMC, Mendonça Filho HTF, Mesquita ET. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This article is part of the thesis of master submitted by Jacqueline Aparecida Borges, from Universidade Federal Fluminense and INCA - RJ. Ethics approval and consent to participate This article does not contain any studies with human participants or animals performed by any of the authors. 1. Kalil Filho R, Hajjar LA, Bacal F, Hoff PM, Diz Mdel P, Galas FR, et al; Grupo de Estudos em Insuficiência Cardíaca da Sociedade Brasileira de Cardiologia (GEIC/SBC); Sociedade Brasileira de Oncologia Clínica; Instituto do Coração – Faculdade de Medicina da Universidade de São Paulo; Instituto do Câncer do Estado de São Paulo – Faculdade de Medicina da Universidade de São Paulo. [I Brazilian guideline for cardio- oncology from Sociedade Brasileira de Cardiologia]. Arq Bras Cardiol. 2011;96(2 Suppl.1):1-52. 2. Lis CG, RodeghierM, Grutsch JF, GuptaD. Distribution and determinants of patient satisfaction in oncology with a focus on heath related quality of life. BMC Heath Serv Res. 2009 Oct 21;9:190. 3. Mota DD, Cruz DA, Pimenta CA. Fadiga: uma análise de conceito. Acta Paul Enferm. 2005;18(3):285-93. 4. Evans WJ, Lambert CP. Physiological basis of fatigue. Am J Phys Med Rehabil. 2007;86(1 Suppl):S29-46. 5. Cella D, Davis K, Breitbart W, Curt G; Fatigue Coalition. Cancer-related fatigue: prevalence of proposed diagnostic criteria in a United States sample of cancer survivors. J Clin Oncol. 2001;19(14):3385-91. 6. Gutstein HB. The biologic basis of fatigue. Cancer. 2000; 92(6 Suppl):1678-83. 7. Mettauer B, Zoll J, Sandchez H, Lampert E, Ribera F, Veksler V, et al. Oxidative capacity of skeletal muscle in heart failure patients versus sedentary or active control subjects J AmColl Cardiol. 2001;38(4):947-54. 8. Alpert CM, Smith MA, Hummel SL, Hummel EK. Symptom burden in heart failure: assement, impact on outcomes, and management. Heart Fail Rev. 2017;22(1):25-39. 9. Brannstrom S, Boman K. Effects of person-central and integrated chronic heart failure and palliative home care. PREFER: a randomized controlled study. Eur J Heart Fail. 2014;16(10):1142-51. 10. Markowitz AJ, RabowMW. Palliative management of fatigue at the close of life: "it feels like my body is just worn out". JAMA 2007;298(2):217. 11. Barsevick AM, Whitmer K, Walker L. In their own words: using the common sense model to analyze patient descriptions of cancer-related fatigue. Oncol Nurs. 2001;28(9):1363-9. References