IJCS | Volume 31, Nº3, May/ June 2018

DOI: 10.5935/2359-4802.20180017 250 ORIGINAL ARTICLE International Journal of Cardiovascular Sciences. 2018;31(3)250-257 Mailing Address: Marcos Antonio Almeida-Santos Avenida Gonçalo Prado Rollemberg, 211, sala: 210. Postal Code: 49010-410, São José, Aracaju, SE - Brazil. E-mail: maasantos@cardiol.br , marcosalmeida2010@yahoo.com.br Spatial Analysis and Mortality Trends Associated with Hypertensive Diseases in the States and Regions of Brazil from 2010 to 2014 Marcos Antonio Almeida-Santos, Beatriz Santana Prado, Deyse Mirelle Souza Santos Programa de Pós-graduação em Saúde e Ambiente da Universidade Tiradentes, Aracaju, SE - Brazil Manuscript received June 09, 2017, revised manuscript October 20, 2017, accepted December 19, 2017. Abstract Background: Systemic Arterial Hypertension (SAH) represents the most relevant worsening factor and one of the major risk factors for cardiovascular diseases. Objectives: To analyze trends in the mortality rate associated with hypertensive diseases in Brazil from 2010 to 2014, for states as well as regions. Methods: An epidemiological studywas performed fromaggregate data obtained in populational strata. Cartographic data of the Brazilian territory in "shapefile" were provided by IBGE. Records of mortality associated with arterial hypertension were obtained in DATASUS, through notifications filtered by category I.10 of the International Classification of Diseases (ICD-10). The criterion of statistical significance was a two-tailed p-value < 0.05. Results: The increase in age was progressively associated with an increase in the mean number of deaths related to hypertensive diseases between the years 2010 and 2014. In the age groups between 50-59 years, 60-69 years, 70- 79 years and 80 or more years, the mean and standard deviation for the mortality rate were, respectively: 15.11% (35.35); 24.14% (55.34); 35.07% (81.03) and 57.87% (139.08). The overall mortality rate per 10,000 inhabitants varied between the regions: north (1.25); northeast (2.69); center-west (2.06); southeast (2.48) and south (2.04). Conclusions: The mortality rate associated with hypertensive diseases was higher in the southeastern and northeastern states of Brazil, and remained stable between 2010 and 2014. Increased age and brown color were predictors of higher mortality. (International Journal of Cardiovascular Sciences. 2018;31(3)250-257) Keywords: Cardiovascular Diseases / mortality; Hypertension / epidemiology; Hypertension / etiology; Ethnicity and Health; Stroke; Epidemiologic Studies. Introduction Cerebrovascular diseases have been classified among thosewith the greatest impact in terms ofmorbimortality. 1 Among the major cardiovascular risk factors, systemic arterial hypertension (SAH) represents the most relevant worsening factor, requiring health actions in order to minimize the factors of impact that are determinant for the populations’ health. 2 The global prevalence of arterial hypertension was 22%, in 2014, in adults aged 18 years and over. 3 SAH is characterized by increased blood pressure levels (≥ 140 and/or 90 mmHg), in which the clinical condition can be caused by several reasons andmay be worsened by other risk factors, such as dyslipidemia, abdominal obesity, glucose intolerance, diabetes mellitus (DM), in addition to other modifiable factors, socioeconomic determinants and inadequate access to health care. 3,4 Several studies point to the influence of ethnic aspects in the emergence of hypertensive diseases. 5 Often it is difficult to dissociate the role represented by an ethnic group of the socioeconomic factors simultaneously active. 6 In Brazil, cerebrovascular mortality rates were higher in black people, followed by brown and white people. 7 About 32.6% of adults and more than 60% of elderly people suffer from high blood pressure in Brazil, which