IJCS | Volume 31, Nº3, May/ June 2018

224 1. Instituto Brasileiro de Geografia e Estatística. (IBGE). Pesquisa Nacional de Saúde 2013: Percepção do estado de saúde, estilos de vida e doenças crônicas. Rio de Janeiro; 2014. 2. World Health Organization. (WHO). Global health observatory data repositor: cardiovascular disease, deaths per 100 000, 2012. [Accessed in 2015 Sept 22]. Available from: http://apps.who.int/gho/data/ node. main.A865CARDIOVASCULAR?lang=en 3. Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD, et al; Joint ESC/ACCF/AHA/WHF Task Force for the Universal Definition of Myocardial Infarction. Third universal definition of myocardial infarction. Circulation. 2012;126(16):2020-35. doi: 10.1161/ CIR.0b013e31826e1058. 4. Piegas LS, TimermanA, Feitosa GS, Nicolau JC, Mattos LA, AndradeMD, et al. VDiretriz da Sociedade Brasileira de Cardiologia sobre tratamento do infarto agudo domiocárdio com supradesnível do segmento ST. Arq Bras Cardiol. 2015;105(2):1-105. doi: http://dx.doi.org/10.5935/abc.20150107. 5. Thygesen K, Alpert JS, Antman E, Bassand JP. Myocardial infarction redefined - A consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction. J AmColl Cardiol. 2000;36(3):959- 69. PMID: 10987628. Erratum in: J AmColl Cardiol 2001 Mar 1;37(3):973. 6. Maznyczka A, Kaier T, Marber M. Troponins and other biomarkers in the early diagnosis of acute myocardial infarction. Postgrad Med J. 2015;91(1076):322-30. doi: 10.1136/postgradmedj-2014-133129. References Cardoso et al. Correlation between coronary lesions and troponin International Journal of Cardiovascular Sciences. 2018;31(3)218-225 Original Article reclassification to a higher risk. O´Donoghue et al., 16 after evaluating several biomarkers, concluded that troponin T was associated with higher TIMI scores. Although the authors did not use hsTn in their study, these data corroborate our findings. Therefore, there is a correlation between hsTn and the complexity of lesions quantified by the anatomical SYNTAX score in ACS patients, and a correlation of this biomarker with the prognostic clinical scores GRACE and TIMI. Thus, despite the limitations in blood collection for troponin measurements, and late admission of patients to the emergency department, troponin was shown to be a biomarker capable of predicting intermediate levels of risk score and higher complexity of coronary lesions, indicating a worse prognosis. Additional studies, including larger samples and the follow-up of future cardiovascular events, are needed to better evaluate and, if possible, to identify the cut-off point for hsTn, indicative of a worse prognosis. Although it was not the aim of the present study, LDL-cholesterol levels were not very increased, as the study population was classified as intermediate risk. Even with borderline cholesterol levels, patients had acute coronary event, which highlights the importance of other associated risk factors. In addition, although this parameter was not measured in the whole sample due to insufficient data, increased c-reactive protein levels were found in our population (reference value < 5 mg/dL in our institution). This indicates a higher inflammation status, whichhas beenwell correlated with increased risk for acute coronary events. Conclusion The present study found a significant moderate positive liner correlation between hsTn levels and the complexity of coronary lesions evaluated by the SYNTAX score. Besides, a weak correlation was found between this biomarker and the TIMI and GRACE clinical prognostic scores. Author contributions Conception and design of the research: Cardoso MR, Silva Junior DG. Acquisition of data: Cardoso MR, Ribeiro EA, Rocha Neto AM. Analysis and interpretation of the data: Cardoso MR, Silva Junior DG, Ribeiro EA, Rocha Neto AM. Statistical analysis: Cardoso MR, Silva Junior DG. Writing of the manuscript: Cardoso MR. Critical revision of themanuscript for intellectual content: Silva Junior DG. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This article is part of the thesis of completion of course work (Residence in Cardiology) submitted by Monique Rodrigues Cardoso, fromUniversidade Federal de Mato Grosso do Sul. Ethics approval and consent to participate This article does not contain any studies with human participants or animals performed by any of the authors.