IJCS | Volume 31, Nº2, March / April 2018

139 0.00 0.10 0.20 0.30 0.40 0.50 0.60 0.70 0.80 0.90 1.00 Sensitivity 0.00 0.10 0.20 0.30 0.40 0.50 0.60 0.70 0.80 0.90 1.00 1 - Specificity Area under the curve = 0.9048 (CI 95%: 0.862-0.954) Figure 1 – Receiver operating characteristic (ROC) curve of the multivariate predictive model of obstructive coronary disease in patients with acute pulmonary edema of unclear origin. 95%CI: 95% confidence interval. Table 5 – Predictors of obstructive coronary disease in patients with acute pulmonary edema of unclear origin Predictors OR ajustada (IC 95%) p-value Isquemic chest pain 2.48 (0.38 – 15.9) 0.339 Diabetes 2.37 (0.85 – 6.58) 0.098 Hypertension 1.70 (0.50 – 5.75) 0.392 History of CAD 13.4 (2.81 – .63.6) 0.001 History of POAD 6.76 (0.63 - 72.5) 0.114 History of Stroke 5.62 (0.86 - 36.7) 0.071 Ejection fraction 0.97 (0.93 - 1.01) 0.100 Segmental myocardial contractility deficit 6.21 (1.92 - 20.1) 0.002 Creatinina ≥ 1.2 mg% 2.08 (0.65 – 6.62) 0.214 Q wave 1.53 (0.45 - 5.21) 0.497 Ultrasensitive troponin (1 st measure ng/ml) 2.76 (0.41 – 18.8) 0.299 BNP 1.01 (0.99 - 1.03) 0.417 * Goodness-of-fit of the model: Hosmer-Lemeshow test - p = 0.378. * Area under the curve “0.905 (95%CI: 0.862-0.954)”. CAD: coronary artery disease; POAD: peripheral obstructive arterial disease; BNP: B-type natriuretic peptide" Barros et al. Acute pulmonary edema. Coronary artery disease. Int J Cardiovasc Sci. 2018;31(2)133-142 Original Article myocardial infarction with ST elevation, due to the greater extent of myocardial involvement. In that study, in a target population of 256 consecutively admitted patients with APE, 3 (1%) had acute myocardial infarction with ST elevation and APE in the emergency room, but they were excluded because the etiology of APE, in this clinical context, is well defined.