IJCS | Volume 31, Nº2, March / April 2018

93 Barbosa et al. Impact of risk factors on MRS costs Int J Cardiovasc Sci. 2018;31(2)90-96 Original Article Table 2 – Definitions of cardiovascular risk factors Risk factor Definition Systemic arterial hypertension Arterial pressure ≥ 140x90 mmHg (measured by the physician) Diabetes mellitus Fasting glucose ≥ 126 mg/dL on more than one occasion or non-fasting glucose ≥ 200 mmHg Dyslipidemia LDL-cholesterol ≥ 130 mg/dL or total cholesterol total ≥ 200 mg/dL or Triglycerides ≥ 150 mg/dL Current smoking Self-reported use of any tobacco product within the last 30 days Past smoking Self-reported use of any tobacco product in the past, and cessation at least 30 days before the study Sedentary lifestyle Practice of physical activities for less than 150 minutes a week Family history of CAD CAD in first-degree relatives younger than 55 years (men) or 65 years (women) Chronic kidney disease Glomerular filtration rate lower than 90 mL/min Obesity Body mass index ≥ 30 kg/m 2 LDL: Low density lipoprotein; CAD: coronary artery disease Continuation Left ventricular function, n Normal 3 17 44 49 21 5 Mild dysfunction 2 7 11 4 5 4 0.998 Moderate dysfunction 2 7 9 10 2 1 Severe dysfunction 0 1 11 15 7 1 Mean left ventricular ejection fraction (%) 56 56 56 56 55 56 0.999 Angiographic data, n LCA lesions 1 11 26 22 7 7 0.112 Three vessel disease 5 23 46 52 24 5 0.453 Hospitalization data Days of hospital stay 22.8 29.8 31.4 34.1 31.1 41.1 0.527 Days of ICU stay 5 5 6 8 8 17 0.080 Duration of ECC (minutes) 115 96 101 99 85 93 0.102 Surgeries without ECC 1 4 3 6 3 1 0.695 BMI: body mass index; CAD: Coronary artery disease; NSTEMI: non-ST segment elevation myocardial infarction; STEMI: ST-elevation acute myocardial infarction; ICU: intensive care unit; LCA: left coronary artery; ECC: extracorporeal circulation Also, we found no significant differences in hospitalization data between the groups. This finding is relevant, since duration of hospital stay and ICU stay are strong determinants of total hospitalization costs. 10 In this study, the micro-costing method enabled a more accurate estimation of the hospitalization costs at patient level, including a more refined analysis of the costs related to medication, laboratory tests, complementary imaging tests, materials and professionals. Clinical scores used to assess complication and mortality risk in MRS, such as EuroSCORE 11 and the STS score, 12 estimate the occurrence of events based on the presence of comorbidities and cardiovascular risk

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