ABC | Volume 113, Nº2, Agosto 2019

Artigo Original Casonatto et al. Citrulina e hipotensão pós-exercício Arq Bras Cardiol. 2019; 113(2):218-228 Este é um artigo de acesso aberto distribuído sob os termos da licença de atribuição pelo Creative Commons 26. Casonatto J, Tinucci T, DouradoAC, PolitoM. Cardiovascular and autonomic responses after exercise sessions with different intensities and durations. Clinics (Sao Paulo). 2011;66(3):453-8. 27. Haley SM, Fragala-Pinkham MA. Interpreting change scores of tests and measures used in physical therapy. Phys Ther. 2006;86(5):735-43. 28. Darter BJ, Rodriguez KM, Wilken JM. Test-retest reliability and minimum detectable change using the K4b2: oxygen consumption, gait efficiency, and heart rate for healthy adults during submaximal walking. Res QExerc Sport. 2013;84(2):223-31. 29. Mann TN, Lamberts RP, Lambert MI. High responders and low responders: factors associated with individual variation in response to standardized training. Sports Med. 2014;44(8):1113-24. 30. Vickers AJ. The use of percentage change from baseline as an outcome in a controlled trial is statistically inefficient: a simulation study. BMC Med Res Methodol. 2001;1:6. 31. Sullivan GM, Feinn R. Using effect size-or why the P value is not enough. J Grad Med Educ. 2012;4(3):279-82. 32. Lakens D. Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs. Front Psychol. 2013 Nov 26;4:863. 33. Luttrell MJ, Halliwill JR. Recovery from exercise: vulnerable state, window of opportunity, or crystal ball? Front Physiol. 2015 Jul 22;6:204. 34. Schwedhelm E, Maas R, Freese R, Jung D, Lukacs Z, Jambrecina A, et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol. 2008;65(1):51-9. 35. Mori M. Regulation of nitric oxide synthesis and apoptosis by arginase and arginine recycling. J Nutr. 2007;137(6 Suppl 2):1616S-20S. 36. McKinley-Barnard S, Andre T, Morita M, Willoughby DS. Combined L-citrulline and glutathione supplementation increases the concentration of markers indicative of nitric oxide synthesis. J Int Soc Sports Nutr. 2015 Jun 10;12:27. 37. Kim IY, Schutzler SE, Schrader A, Spencer HJ, Azhar G, DeutzNE, et al. Acute ingestion of citrulline stimulates nitric oxide synthesis but does not increase blood flow in healthy young and older adults with heart failure. Am J Physiol Endocrinol Metab. 2015;309(11):E915-24. 38. BaileySJ,BlackwellJR,LordT,VanhataloA,WinyardPG,JonesAM. l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans. J Appl Physiol (1985). 2015;119(4):385-95. 39. Ochiai M, Hayashi T, Morita M, Ina K, Maeda M, Watanabe F, et al. Short- term effects of L-citrulline supplementation on arterial stiffness in middle- aged men. Int J Cardiol. 2012;155(2):257-61. 40. WongA,Alvarez-AlvaradoS, JaimeSJ,KinseyAW,SpicerMT,MadzimaTA,et al.Combinedwhole-bodyvibrationtrainingand l-citrullinesupplementation improves pressure wave reflection in obese postmenopausal women. Appl Physiol Nutr Metab. 2016;41(3):292-7. 41. Hecksteden A, Kraushaar J, Scharhag-Rosenberger F, Theisen D, Senn S, Meyer T. Individual response to exercise training - a statistical perspective. J Appl Physiol (1985). 2015;118(12):1450-9. 42. Swinton PA, Hemingway BS, Saunders B, Gualano B, Dolan E. A statistical framework to interpret individual response to intervention: paving the way for personalizednutritionandexerciseprescription.FrontNutr.2018May28;5:41. 228

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