ABC | Volume 112, Nº5, Maio 2019

Ponto de Vista Souza et al. Macrófagos residentes e o ritmo cardíaco Arq Bras Cardiol. 2019; 112(5):588-591 Este é um artigo de acesso aberto distribuído sob os termos da licença de atribuição pelo Creative Commons 8. Vozzi C, Dupont E, Coppen SR, Yeh HI, Severs NJ. Chamber-related differences in connexin expression in the human heart. J Mol Cell Cardiol. maio de 1999;31(5):991–1003. 9. Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, et al. Macrophages Facilitate Electrical Conduction in the Heart. Cell. 2017;169(3):510-22.e20. 10. Rosenthal N. A guardian of the heartbeat. NEngl J Med. 2017; 377(1):84–6. 11. Monnerat G, Alarcón ML, Vasconcellos LR, Hochman-Mendez C, Brasil G, Bassani RA, et al. Macrophage-dependent IL-1 β production induces cardiac arrhythmias in diabetic mice. Nat Commun. 2016;7:13344. 12. Held C, White HD, Stewart RAH, Budaj A, Cannon CP, Hochman JS, et al. Inflammatory Biomarkers Interleukin-6 and C-Reactive Protein and Outcomes in Stable Coronary Heart Disease: Experiences From the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) Trial. J AmHeart Assoc. 2017;6(10):pii-e005077. 13. Ridker PM, Libby P, MacFadyen JG, Thuren T, Ballantyne C, Fonseca F, et al. Modulation of the interleukin-6 signalling pathway and incidence rates of atherosclerotic events and all-cause mortality: analyses from the Canakinumab Anti-Inflammatory Thrombosis Outcomes Study (CANTOS). Eur Heart J. 2018;39(38):3499–507. 14. Ridker PM, Lüscher TF. Anti-inflammatory therapies for cardiovascular disease. Eur Heart J. 2014;35(27):1782–91. 15. Cruz JS, Machado FS, Ropert C, Roman-Campos D. Molecular mechanisms ofcardiacelectromechanicalremodelingduringChagasdisease:RoleofTNF and TGF- β . Trends Cardiovasc Med. 2017;27(2):81–91. 16. MerxMW,WeberC.Sepsisandtheheart.Circulation.2007;116(7):793–802. 17. Wang HE, Moore JX, Donnelly JP, Levitan EB, Safford MM. Risk of Acute Coronary Heart Disease After Sepsis Hospitalization in the REasons for Geographic and Racial Differences in Stroke (REGARDS) Cohort. Clin Infect Dis. 2017;65(1):29–36. 18. Zannad F. Rising incidence of heart failure demands action. Lancet. 2018;391(10120):518–9. 19. Patel B, Bansal SS, Ismahil MA, Hamid T, Rokosh G, Mack M, et al. CCR2+ Monocyte-Derived Infiltrating Macrophages Are Required for Adverse Cardiac RemodelingDuringPressureOverload.JACCBasicTranslSci.2018;3(2):230-44. 20. Zupančič E, Fayad ZA, Mulder WJM. Cardiovascular Immunotherapy and the Role of Imaging. Arterioscler Thromb Vasc Biol. 2017;37(11):e167–71. 21. Martini E, Stirparo GG, Kallikourdis M. Immunotherapy for cardiovascular disease. J Leukoc Biol. 2018;103(3):493–500. 591