ABC | Volume 112, Nº1, Janeiro 2019

Artigo Original Jevjdovic et al Estresse pré-natal afeta ADRB1 no coração de ratos Arq Bras Cardiol. 2019; 112(1):67-75 Este é um artigo de acesso aberto distribuído sob os termos da licença de atribuição pelo Creative Commons 30. Steinfath M, Lavicky J, Schmitz W, Scholz H, Doring V, Kalmar P. Regional distribution of beta 1- and beta 2-adrenoceptors in the failing and nonfailing human heart. Eur J Clin Pharmacol. 1992;42(6):607-11. 31 Lindenfeld J, Cleveland JC, Jr., Kao DP, White M, Wichman S, Bristow JC, et al. Sex-related differences in age-associated downregulation of human ventricular myocardial beta1-adrenergic receptors. J Heart Lung Transplant. 2016;35(3):352-61. 32. Lathers CM, Levin RM, Spivey WH. Regional distribution of myocardial beta-adrenoceptors in the cat. Eur J Pharmacol. 1986;130(1-2):111-7. 33. Izumi Y, Okatani H, Shiota M, Nakao T, Ise R, Kito G, et al. Effects of metoprolol on epinephrine-induced takotsubo-like left ventricular dysfunction in non-human primates. Hypertens Res. 2009;32(5):339-46. 34. White M, Roden R, Minobe W, Khan MF, Larrabee P, Wollmering M, et al. Age-related changes in beta-adrenergic neuroeffector systems in the human heart. Circulation. 1994;90(3):1225-38. 35. Paur H,Wright PT, Sikkel MB, Tranter MH, Mansfield C, O’Gara P, et al. High levels of circulating epinephrine trigger apical cardiodepression in a beta2- adrenergic receptor/Gi-dependent manner: a new model of Takotsubo cardiomyopathy. Circulation. 2012;126(6):697-706. 36. Bristow MR, Ginsburg R, Umans V, Fowler M, Minobe W, Rasmussen R, et al. Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes tomusclecontractionandselectivebeta1-receptordown-regulation inheart failure. Circ Res. 1986;59(3):297-309. 37. Xiao RP, Tomhave ED, Wang DJ, Ji X, Boluyt MO, Cheng H, et al. Age- associated reductions in cardiac beta1- and beta2-adrenergic responses without changes in inhibitory G proteins or receptor kinases. J Clin Invest. 1998;101(6):1273-82. 38. Lyon AR, Rees PS, Prasad S, Poole-Wilson PA, Harding SE. Stress (Takotsubo) cardiomyopathy--a novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning. Nat Clin Pract Cardiovasc Med. 2008;5(1):22-9. 39. Colom B, Oliver J, Roca P, Garcia-Palmer FJ. Caloric restriction and gender modulate cardiac muscle mitochondrial H2O2 production and oxidative damage. Cardiovasc Res. 2007;74(3):456-65. 75