ABC | Volume 112, Nº1, Janeiro 2019

Comunicação Breve Bertolici et al Diuréticos e losartana no estágio I da hipertensão Arq Bras Cardiol. 2019; 112(1):87-90 Em conclusão, na hipertensão estágio I a redução da pressão arterial está associada à melhora dos parâmetros ecocardiográficos de lesão de órgãos-alvo, com um remodelamento favorável do VE obtido com diuréticos ou losartana como estratégia de tratamento inicial. Contribuição dos autores Concepção e desenho da pesquisa, análise e interpretação dos dados e análise estatística: Bertoluci C, Foppa M, Fuchs SC, Fuchs FD; obtenção de dados: Bertoluci C, Foppa M; obtenção de financiamento: Fuchs SC, Fuchs FD; redação do manuscrito e revisão crítica do manuscrito quanto ao conteúdo intelectual importante: Bertoluci C, FoppaM, Santos ABS, Fuchs SC, Fuchs FD. Potencial conflito de interesses Declaro não haver conflito de interesses pertinentes. Fontes de financiamento O presente estudo foi financiado pelo DECIT, CNPq, FINEP, IATS e FIPE do Hospital de Clínicas de Porto Alegre. Vinculação acadêmica Este artigo é parte de tese de Doutorado de Carolina Bertoluci pela Universidade Federal do Rio Grande do Sul. 1. Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE Jr, Drazner MH, et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the AmericanCollege of Cardiology Foundation/AmericanHeart Association Task Force on practice guidelines. Circulation. 2013;128(16):e240-327. 2. VerdecchiaP,CariniG,CircoA,DovelliniE,GiovanniniE,LombardoM,etal. Left ventricular mass and cardiovascular morbidity in essential hypertension: the MAVI study. J Am Coll Cardiol. 2001;38(7):1829-35. 3. Pierdomenico SD, LapennaD, Bucci A, Manente BM, Cuccurullo F, Mezzetti A.Prognosticvalueof leftventricularconcentricremodeling inuncomplicated mild hypertension. Am J Hypertens. 2004;17(11 Pt 1):1035-9. 4. Halley CM, Houghtaling PL, Khalil MK, Thomas JD, Jaber WA. Mortality rate in patients with diastolic dysfunction and normal systolic function. Arch Intern Med. 2011;171(12):1082-7. 5. Fagard RH, Celis H, Thijs L, Wouters S. Regression of left ventricular mass by antihypertensive treatment: ameta-analysis of randomized comparative studies. Hypertension. 2009;54(5):1084-91. 6. Fuchs FD, Scala LC, Vilela-Martin JF, de Mello RB, Mosele F, Whelton PK, et al. Effectiveness of chlorthalidone/amiloride versus losartan in patients with stage I hypertension: results from the PREVER-treatment randomized trial. J Hypertens. 2016;34(4):798-806. 7. James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 evidence-based guideline for themanagement of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8) JAMA. 2014;311(5):507–20. 8. Bertoluci C, Foppa M, Santos ABS, Branchi TV, Fuchs SC, Fuchs FD. Echocardiographic left ventricular reverse remodeling after 18 months of antihypertensive treatment in stage I hypertension. Results from the PREVER- treatment study. Am J Hypertens;31(3):321-8. 9. Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2015;28(1):1-39.e14. 10. PietroDA,VoelkelAG,RayBJ,ParisiAF.Reproducibilityofechocardiography. A study evaluating the variability of serial echocardiographicmeasurements. Chest.1981;79(1):29-32. 11. Liebson PR, Grandits G, Prineas R, Dianzumba S, Flack JM, Cutler JA, et al. Echocardiographic correlates of left ventricular structure among 844mildly hypertensivemen andwomen in the Treatment of MildHypertension Study (TOMHS). Circulation. 1993;87(2):476-86. 12. Devereux RB, Dahlöf B, Gerdts E, Boman K, NieminenMS, Papademetriou V, et al. Regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial. Circulation. 2004;110(11):1456-62. 13. Galzerano D, Tammaro P, Cerciello A, Breglio R, MallardoM, Lama D, et al. Freehand three-dimensional echocardiographic evaluation of the effect of telmisartan compared with hydrochlorothiazide on left ventricular mass in hypertensive patients with mild-to-moderate hypertension: a multicentre study. J HumHypertens. 2004;18(1):53-9. Referências Este é um artigo de acesso aberto distribuído sob os termos da licença de atribuição pelo Creative Commons 90