ABC | Volume 111, Nº6, Dezembro 2018

Artigo Original Radaelli et al Estatinas para tratar crianças: uma meta-análise Arq Bras Cardiol. 2018; 111(6):810-821 23. van der Graaf A, Cuffie-Jackson C, Vissers MN, Trip MD, Gagné C, Shi G, et al. Efficacy and safety of coadministration of ezetimibe and simvastatin in adolescents with heterozygous familial hypercholesterolemia. J Am Coll Cardiol. 2008;52(17):1421-9. 24. BraamskampMJ, Stefanutti C, Langslet G, Drogari E,Wiegman A, Hounslow N, et al. “Efficacy and safety of pitavastatin in children and adolescents at high future cardiovascular risk.” J Pediatr. 2015;167(2):338-43. 25. Koeijvoets KC, Rodenburg J, Hutten BA, Wiegman A, Kastelein JJ, Sijbrands EJ. Low-density lipoprotein receptor genotype and response to pravastatin in childrenwith familial hypercholesterolemia: substudy of an intima-media thickness trial. Circulation. 2005;112(20):3168-73. 26. Rodenburg J, Vissers MN, Wiegman A, van Trotsenburg AS, van der Graaf A, de Groot E, et al. Statin treatment in children with familial hypercholesterolemia: the younger, the better. Circulation 2007;116(6):664-8. 27. Ryu SK, Hutten BA, Vissers MN, Wiegman A, Kastelein JJ, Tsimikas S. Lipoprotein-associated phospholipase A2mass and activity in childrenwith heterozygous familial hypercholesterolemia and unaffected siblings: effect of pravastatin. J Clin Lipidol 2011;5(1):50-6. 28. Braamskamp MJ, Tsimikas S, Wiegman A, Kastelein JJ, Hutten BA. Statin therapy and secretory phospholipase A(2) in children with heterozygous familial hypercholesterolemia. Atherosclerosis 2013;229(2):404-7. 29. Lambert M, Lupien PJ, Gagné C, Lévy E, Blaichman S, Langlois S, et al. Treatment of familial hypercholesterolemia in children and adolescents: effect of lovastatin. Pediatrics. 1996;97(5):619-28. 30. LawMR, WaldNJ, Rudnicka AR. Quantifying effect of statins on lowdensity lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis. Bmj. 2003;326(7404):1423. 31. Watts GF, Gidding S, Wierzbicki AS, Toth PP, Alonso R, Brown WV, et al. Integrated guidance on the care of familial hypercholesterolemia from the International FH Foundation. J Clin Lipidol. 2014;8(3):148-72. 32. Daniels SR, Gidding SS, de Ferranti SD; National Lipid Association Expert Panel on Familial Hypercholesterolemia.. Pediatric aspects of familial hypercholesterolemias: recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. J Clin Lipidol. 2011;5(3 Suppl):S30-7. 33. Vuorio A, Kuoppala J, Kovanen PT, Humphries SE, Strandberg T, Tonstad S, et al. Statins for children with familial hypercholesterolemia. Cochrane Database Syst Rev. 2010;7(7):CD006401. 34. DescampsOS,TenoutasseS,StephenneX,GiesI,BealouyeV,LebrethonMC, et al. Management of familial hypercholesterolemia in children and young adults: consensus paper developed by a panel of lipidologists, cardiologists, paediatricians, nutritionists, gastroenterologists, general practitioners and a patient organization. Atherosclerosis. 2011;218(2):272-80. 35. GiddingSS,ChampagneMA,deFerrantiSD,Defesche J, ItoMK,Knowles JW, et al. The Agenda for Familial Hypercholesterolemia A Scientific Statement From the AmericanHeart Association. Circulation. 2015;132(22):2167-92. 36. Braamskamp MJ, Kusters DM, Wiegman A, Avis HJ, Wijburg FA, Kastelein JJ, et al. Gonadal steroids, gonadotropins and DHEAS in young adults with familial hypercholesterolemiawho had initiated statin therapy in childhood. Atherosclerosis. 2015;241(2):427-32. 818