ABC | Volume 111, Nº2, Agosto 2018

Artigo Original Farsky et al Inflamação persistente após stent Arq Bras Cardiol. 2018; 111(2):134-141 Arnoni RT, Almeida AFS, Issa M, Lima PHO, Higuchi ML, Lin-Wang HT; Análise estatística: Lin‑Wang HT; Obtenção de financiamento: Farsky PS, Lima PHO; Redação do manuscrito: Farsky PS, Lin‑Wang HT; Revisão crítica do manuscrito quanto ao conteúdo intelectual importante: Farsky PS, Hirata MH, Arnoni RT, Almeida AFS, Issa M, Lin‑Wang HT. Potencial conflito de interesses Declaro não haver conflito de interesses pertinentes. Fontes de financiamento O presente estudo foi financiado pela FAPESP. Vinculação acadêmica Este artigo é parte de tese de Pós-Doutorado de Pedro Silvio Farsky pelo Instituto Dante Pazzanese de Cardiologia / Universidade de São Paulo. Aprovação ética e consentimento informado Este estudo foi aprovado pelo Comitê de Ética do Instituto de Cardiologia Dante Pazzanese sob o número de protocolo 4059-2011. Todos os procedimentos envolvidos nesse estudo estão de acordo com a Declaração de Helsinki de 1975, atualizada em 2013. O consentimento informado foi obtido de todos os participantes incluídos no estudo. 1. Gaudino M, Cellini C, Pragliola C, Trani C, Burzotta F, Schiavoni G, et al. Arterial versus venous bypass grafts in patients with in-stent restenosis. Circulation. 2005;112(9 Suppl):I265-9. 2. Gomes WJ, Buffolo E. Coronary stenting and inflammation: implications for furthersurgicalandmedicaltreatment.AnnThoracSurg.2006;81(5):1918-25. 3. Hassan A, Buth KJ, Baskett RJ, Ali IS, Maitland A, Sullivan JA, et al. The association between prior percutaneous coronary intervention and short-term outcomes after coronary artery bypass grafting. Am Heart J. 2005;150(5):1026-31. 4. Rao C, Stanbridge Rde L, Chikwe J, Pepper J, Skapinakis P, AzizO, et al. Does previous percutaneous coronary stenting compromise the long-termefficacy of subsequent coronary artery bypass surgery? Amicrosimulation study. Ann Thorac Surg. 2008;85(2):501-7. 5. Thielmann M, Leyh R, Massoudy P, Neuhäuser M, Aleksic I, Kamler M, et al. Prognostic significance of multiple previous percutaneous coronary interventions in patients undergoing elective coronary artery bypass surgery. Circulation. 2006;114(1 Suppl):I441-7. 6. Thielmann M, Neuhauser M, Knipp S, Kottenberg-Assenmacher E, Marr A, Pizanis N, et al. Prognostic impact of previous percutaneous coronary intervention in patients with diabetes mellitus and triple-vessel disease undergoing coronary artery bypass surgery. J Thorac Cardiovasc Surg. 2007;134(2):470-6. 7. Ueki C, Sakaguchi G, Akimoto T, Shintani T, Ohashi Y, Sato H. Influence of previous percutaneous coronary intervention on clinical outcome of coronary artery bypass grafting: a meta-analysis of comparative studies. Interact Cardiovasc Thorac Surg. 2015;20(4):531-7. 8. Yap CH, Yan BP, Akowuah E, Dinh DT, Smith JA, Shardey GC, et al. Does prior percutaneous coronary intervention adversely affect early and mid-term survival after coronary artery surgery? JACC Cardiovasc Interv. 2009;2(8):758-64. 9. Borges JC, Lopes N, Soares PR, Góis AF, Stolf NA, Oliveira SA, et al. Five-year follow-up of angiographic disease progression after medicine, angioplasty, or surgery. J Cardiothorac Surg. 2010 Oct 26;5:91. 10. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002 June 18;3(7):RESEARCH0034. 11. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25(4):402-8. 12. Wu M, Gu X, Li X, Li Y, Zhou H, Lu G, et al. C-reactive protein and inflammatory cytokines during percutaneous coronary intervention. J Vasc Res. 2016;53(1-2):39-48. 13. Yoneda S, Abe S, Kanaya T, Oda K, Nishino S, KageyamaM, et al. Late-phase inflammatory response as a feature of in-stent restenosis after drug-eluting stent implantation. Coron Artery Dis. 2013;24(5):368-73. 14. KimWJ, Kang YJ, Suk K, Park JE, Kwon BS, LeeWH. Comparative analysis of the expression patterns of various TNFSF/TNFRSF in atherosclerotic plaques. Immunol Invest. 2008;37(4):359-73. 15. DepreC,RibichiniF,WijnsW.Morphologicalanalysisofatheroscleroticplaque retrievedbycoronaryatherectomy.Semin IntervCardiol.2000;5(4):175-84. 16. Aggarwal BB. Signalling pathways of the TNF superfamily: a double-edged sword. Nat Rev Immunol. 2003;3(9):745-56. 17. Gerdes N, Seijkens T, Lievens D, Kuijpers MJ, Winkels H, Projahn D, et al. Platelet CD40 exacerbates atherosclerosis by transcellular activation of endothelial cells and leukocytes. Arterioscler Thromb Vasc Biol. 2016;36(3):482-90. 18. Wang P, Mariman E, Renes J, Keijer J. The secretory function of adipocytes in the physiology of white adipose tissue. J Cell Physiol. 2008;216(1):3-13. 19. Kuryszko J, Slawuta P, Sapikowski G. Secretory function of adipose tissue. Pol J Vet Sci. 2016;19(2):441-6. 20. Lee WH, Kim SH, Lee Y, Lee BB, Kwon B, Song H, et al. Tumor necrosis factor receptor superfamily 14 is involved in atherogenesis by inducing proinflammatory cytokines and matrix metalloproteinases. Arterioscler Thromb Vasc Biol. 2001;21(12):2004-10. 21. SchuettH,LuchtefeldM,GrothusenC,GroteK,SchiefferB.Howmuch istoo much? Interleukin-6 and its signalling in atherosclerosis. Thromb Haemost. 2009;102(2):215-22. 22. Hartman J, FrishmanWH. Inflammation and atherosclerosis: a reviewof the role of interleukin-6 in the development of atherosclerosis and the potential for targeted drug therapy. Cardiol Rev. 2014;22(3):147-51. 23. Kazmierczak E, Grajek S, Kowal J, Chmara E, Grygier M, Pyda M, et al. Prognostic usefulness of IL-6 and VEGF for the occurrence of changes in coronary arteries of patients with stable angina and implanted stents. Eur Rev Med Pharmacol Sci. 2014;18(15):2169-75. 24. Szkodzinski J, Blazelonis A, Wilczek K, Hudzik B, Romanowski W, Gasior M, et al. The role of interleukin-6 and transforming growth factor-beta1 in predictingrestenosiswithinstented infarct-relatedartery. Int J Immunopathol Pharmacol. 2009;22(2):493-500. Referências Este é um artigo de acesso aberto distribuído sob os termos da licença de atribuição pelo Creative Commons 141