ABC | Volume 111, Nº2, Agosto 2018

Diretrizes 3ª Diretriz Brasileira de Transplante Cardíaco Arq Bras Cardiol. 2018; 111(2):230-289 131. Kobashigawa JA, Renlund DG, Gerosa G, Almenar L, Eisen HJ, Keogh AM, et al; ERL2401 Heart Study Investigators. Similar efficacy and safety of enteric-coated mycophenolate sodium (EC-MPS, myfortic) comparedwithmycophenolatemofetil (MMF) in de novo heart transplant recipients:resultsofa12-month,single-blind,randomized,parallel-group, multicenter study. J Heart Lung Transplant. 2006;25(8):935-41. doi: 10.1016/j.healun.2006.04.005. 132. Lehmkuhl H, Hummel M, Kobashigawa J, Ladenburger S, Rothenburger M, Sack F, et al. Enteric-coated mycophenolate-sodium in heart transplantation: efficacy, safety, and pharmacokinetic compared with mycophenolate mofetil. Transplant Proc. 2008;40(4):953-5. doi: 10.1016/j.transproceed.2008.03.046. 133. Bacal F, Silva CP, Pires PV, Mangini S, Fiorelli AI, Stolf NG, et al. Transplantation for Chagas' disease: an overview of immunosuppression and reactivation in the last two decades. Clin Transplant. 2010;24(2):E29- 34. doi: 10.1111/j.1399-0012.2009.01202.x. 134. Keogh A, Richardson M, Ruygrok P, Spratt P, Galbraith A, O'Driscoll G, et al. Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years: a randomized clinical trial. Circulation. 2004;110(17):2694-700. doi: 10.1161/01. CIR.0000136812.90177.94. 135. García-Luque A, Cordero E, Torelló J, Lage E, Juan JM, Cisneros JM, et al. Sirolimus-associated pneumonitis in heart transplant recipients. Ann Pharmacother. 2008;42(7):1143-5. doi: 10.1345/aph.1L044. 136. KhalifeWI, Kogoj P, Kar B. Sirolimus-induced alveolar hemorrhage. J Heart Lung Transplant. 2007;26(6):652-7. doi: 10.1016/j.healun.2007.02.010. 137. Eisen HJ, Kobashigawa J, Starling RC, Pauly DF, Kfoury A, Ross H, et al. Everolimus versus mycophenolate mofetil in heart transplantation: a randomized, multicenter trial. Am J Transplant. 2013;13(5):1203-16. doi: 10.1111/ajt.12181. 138. Watanabe T, Seguchi O, Nishimura K, Fujita T, Murata Y, Yanase M, et al. Suppressive effects of conversion from mycophenolate mofetil to everolimus for the development of cardiac allograft vasculopathy in maintenance of heart transplant recipients. Int J Cardiol. 2016 Jan 15;203:307-14. doi: 10.1016/j.ijcard.2015.10.082. 139. Costanzo MR, Dipchand A, Starling R, Anderson A, Chan M, Desai S, et al; International Society of Heart and Lung Transplantation Guidelines. The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Heart Lung Transplant. 2010;29(8):914-56. doi: 10.1016/j.healun.2010.05.034. 140. Mattner F, Kola A, Fischer S, Becker T, Haverich A, Simon A, et al. Impact of bacterial and fungal donor organ contamination in lung, heart-lung, heart and liver transplantation. Infection. 2008;36(3):207-12. doi: 10.1007/ s15010-007-7157-x. 141. Kotton CN, Kumar D, Caliendo AM, Asberg A, Chou S, Danziger-Isakov L, et al; Transplantation Society International CMV Consensus Group. Updated international consensus guidelines on the management of cytomegalovirus in solid-organ transplantation. Transplantation. 2013;96(4):333-60. doi: 10.1097/TP.0b013e31829df29d. 142. Wilck MB, Zuckerman RA; AST Infectious Diseases Community of Practice. Herpes simplex virus in solid organ transplantation. Am J Transplant. 2013 Mar;13 Suppl 4:121-7. doi: 10.1111/ajt.12105. 143. Derouin F, Pelloux H. ESCMID Study Group on Clinical Parasitology. Prevention of toxoplasmosis in transplant patients. Clin Microbiol Infect. 2008;14(12):1089-101. doi: 10.1111/j.1469-0691.2008.02091.x. 144. Strabelli TM, Siciliano RF, Vidal Campos S, Bianchi Castelli J, Bacal F, Bocchi EA, et al. Toxoplasma gondii myocarditis after adult heart transplantation: successful prophylaxis with pyrimethamine. J Trop Med. 2012;2012:853562. doi: 10.1155/2012/853562. 145. Martin SI, Fishman JA; AST Infectious Diseases Community of Practice. Pneumocystis pneumonia in solid organ transplantation. Am J Transplant. 2013 Mar;13 Suppl 4:272-9. doi: 10.1111/ajt.12119. 146. Schwartz BS, Mawhorter SD; AST Infectious diseases community of practice. Parasitic infections in solid organ transplantation. Am J Transplant. 2013 Mar;13 Suppl 4:280-303. doi: 10.1111/ajt.12120. 147. Danziger-Isakov L, Kumar D; AST Infectious Diseases Community of Practice. Vaccination in solid organ transplantation. Am J Transplant. 2013 Mar;13 Suppl 4:311-7. doi: 10.1111/ajt.12122. 148. Danzinger-Isakov L, Kumar D; AST Infectious Diseases Community of Practice. Guidelines for vaccination of solid organ transplant candidates and recipients. Am J Transplant. 2009 Dec;9 Suppl 4:S258-62. doi: 10.1111/j.1600-6143.2009.02917.x. 149. Stehlik J, Starling RC, Movsesian MA, Fang JC, Brown RN, Hess ML, et al; Cardiac Transplant Research Database Group. Utility of long-term surveillance endomyocardial biopsy: a multi-institutional analysis. J Heart Lung Transplant. 2006;25(12):1402-9. doi: 10.1016/j. healun.2006.10.003. 150. Orrego CM, Cordero-Reyes AM, Estep JD, Loebe M, Torre-Amione G. Usefulness of routine surveillance endomyocardial biopsy 6months after heart transplantation. J Heart Lung Transplant. 2012;31(8):845-9. doi: 10.1016/j.healun.2012.03.015. 151. Badano LP, Miglioranza MH, Edvardsen T, Colafranceschi AS, Muraru D, Bacal F, et al. European Association of Cardiovascular Imaging/ Cardiovascular Imaging Department of the Brazilian Society of Cardiology recommendations for the use of cardiac imaging to assess and follow patients after heart transplantation. Eur Heart J Cardiovasc Imaging. 2015;16(9):919-48. doi: 10.1093/ehjci/jev139. 152. Reed EF, Hong B, Ho E, Harris PE,Weinberger J, Suciu-Foca N. Monitoring of soluble HLA alloantigens and anti-HLA antibodies identifies heart allograft recipients at risk of transplant-associated coronary artery disease. Transplantation. 1996;61(4):566-72. PMID: 8610382. 153. Kaczmarek I, Deutsch M, Kauke T, Beiras-Fernandez A, Schmoeckel M, Vicol C, et al. Donor-specific HLA alloantibodies: long-term impact on cardiac allograft vasculopathy andmortality after heart transplant. ExpClin Transplant. 2008;6(3):229-35. PMID: 18954302. 154. Ho EK, Vlad G, Vasilescu ER, de la Torre L, Colovai AI, Burke E, et al. Pre- and posttransplantation allosensitization in heart allograft recipients:major impact of de novo alloantibody production on allograft survival. Hum Immunol. 2011;72(1):5-10. doi: 10.1016/j.humimm.2010.10.013. 155. ReinsmoenNL, Lai CH, Mirocha J, Cao K, Ong G, NaimM, et al. Increased negative impact of donor HLA-specific together with non-HLA-specific antibodies on graft outcome. Transplantation. 2014;97(5):595-601. doi: 10.1097/01.TP.0000436927.08026.a8. 156. Fidler SJ, Irish AB, LimW, Ferrari P,Witt CS, Christiansen FT. Pre-transplant donor specific anti-HLA antibody is associated with antibody-mediated rejection, progressive graft dysfunction and patient death. Transpl Immunol. 2013;28(4):148-53. doi: 10.1016/j.trim.2013.05.001. 157. SusalC,Ovens J,MahmoudK,DöhlerB,SchererS,RuhenstrothA,etal.No association of kidney graft loss with human leukocyte antigen antibodies detected exclusively by sensitive Luminex single-antigen testing: a Collaborative Transplant Study report. Transplantation. 2011;91(8):883-7. doi: 10.1097/TP.0b013e3182100f77. 158. Smith JD, Banner NR, Hamour IM, Ozawa M, Goh A, Robinson D, et al. De novo donor HLA-specific antibodies after heart transplantation are an independent predictor of poor patient survival. 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