ABC | Volume 115, Nº2, August 2020
Original Article Cadore et al. Preventive Angioplasty in Myocardial Infarction Arq Bras Cardiol. 2020; 115(2):229-237 Of the total 85 patients, 58 (68.2%) were treated with CR and 27 (31.8%) were treated with culprit-artery-only revascularization. The mean age was 62±12 years, and 61 (71.8%) participants were male. Inferior infarction occurred in 42 (49.4%) patients, followed by anterior infarction in 37 (43.5%). Seventy-one (83.5%) patients were rated as Killip class I at admission, and 68 (78.8%) had double-vessel disease. The LAD was responsible for 32 (37.6%) infarctions, while the lesion was found to be related to the acute myocardial infarction in 36 (42.4%) patients. Finally, 17 (20.0%) patients had no significant lesions in that artery, as described in Table 1. There was no statistically significant difference between the two revascularization strategies in any of the characteristics that were analyzed, including door-to-balloon time. Coronary Intervention Of the 58 patients who were given the CR strategy, 6 (10.3%) were fully treated at the index event – all of them had double-vessel disease, including four patients with the diagonal branch and two patients with the LAD as the nonculprit artery that was treated. Fifty-two patients were treated with staged revascularization of the nonculprit artery – 38 at the initial admission and 14 at a subsequent admission. The mean time between primary PCI and the new procedure was 13±11 days, ranging from 3 to 40 days. Detailed treatment (including PCI and drug therapy) is described in Table 2. Bare-metal stents were implanted in 76 (89.4%) patients. All patients were given dual antiplatelet therapy and statin Table 1 – Clinical and demographic characteristics of the study population (n = 85) Revascularization strategy Overall Complete Incomplete p Center 0.43 1 28 (32.9%) 17 (60.7%) 11 (39.3%) 2 57 (67.1%) 41 (71.9%) 16 (28.1%) Age (years) 62±12 62.7±12 60.6±13 0.46 Male 61 (71.8%) 42 (72.4%) 19 (74.0%) 0.99 White 80 (94.1%) 55 (94.8%) 25 (92.6%) 0.99 Previous history Hypertension 54 (63.5%) 37 (63.8%) 17 (63.0%) 0.99 Diabetes 22 (25.9%) 14 (24.1%) 8 (29.6%) 0.79 Smoking 26 (30.6%) 21 (36.2%) 5 (18.5%) 0.16 Previous CAD 10 (11.8%) 5 (8.6%) 5 (18.5%) 0.34 AMI location 0.94* Anterior 37 (43.5%) 26 (44.8%) 11 (40.7%) Inferior 42 (49.4%) 28 (48.3%) 14 (51.9%) Lateral 6 (7.1%) 4 (6.9%) 2 (7.4%) LBBB 4 (4.7%) 2 (3.4%) 2 (7.4%) 0.80* No. of stenoses 0.87 2 67 (78.8%) 46 (79.3%) 21 (77.8%) 3 18 (21.1%) 12 (20.7%) 6 (22.2%) LAD 0.28 Culprit 32 (37.6%) 22 (37.9%) 10 (37.0%) Nonculprit 36 (42.4%) 27 (46.6%) 9 (33.3%) No lesion 17 (20.0%) 9 (15.5%) 8 (29.6%) LVEF < 50% 41 (48.2%) 25 (43.1%) 16 (59.3%) 0.25 Killip class 0.62* 1 71 (83.5%) 50 (86.2%) 21 (77.8%) 2 7 (8.2%) 4 (6.9%) 3 (11.1%) 3 7 (8.2%) 4 (6.9%) 3 (11.1%) Values are mean ± standard deviation or absolute and relative frequency. p: probability value; analysis of variance was used for age; for the others, Pearson’s chi- square text or *Fischer’s exact test was used. CAD: coronary artery disease; AMI: acute myocardial infarction; LBBB: left bundle branch block; LAD: left anterior descending artery; LVEF: left ventricular ejection fraction. 231
Made with FlippingBook
RkJQdWJsaXNoZXIy MjM4Mjg=