ABC | Volume 114, Nº6, June 2020

Original Article Yang et al Chemotherapy-related coronary-artery disease Arq Bras Cardiol. 2020; 114(6):1004-1012 Table 1 – Patient characteristics stratified by history of chemotherapy Characteristic Chemotherapy group (n = 36) Non-chemotherapy group (n = 58) p value Gender 0.6257 Male 27 (75.00%) 46 (79.31%) Female 9 (25.00%) 12 (20.69%) Age at CAG (years) 0,077 <60 3 (8,33%) 13 (22,41%) ≥60 33 (91.67%) 45 (77,59%) Interval time from cancer diagnosis to CAG (years) 0.000 ≤2 17 (47.22%) 48 (82.76%) >2 19 (52.78%) 10 (17.24%) Types of lung cancer 0.081 Non-small cell lung cancer 30 (83.33%) 55 (94.83%) Small cell lung cancer 6 (16.67%) 3 (5.17%) Regimens of chemotherapy NA Platinum + 28 (77.78%) -- Tyrosine kinase inhibitors only 5 (13.89%) -- Not-verified regimens 3(8.33%) -- Radiotherapy <0.0001 No 19 (52.78%) 54 (93.10%) Yes 17 (47.22%) 4 (6.90%) BMI 24.81 ± 2.89 25.32 ± 2.79 0.3944 Hypertension No 12 (34.29%) 27 (46.55%) Yes 23 (65.71%) 31 (53.45%) Diabetes 0.9343 No 28 (80.00%) 46 (80.70%) Yes 7 (20.00%) 11 (19.30%) Hyperlipidemia 0.5157 No 29 (82.86%) 50 (87.72%) Yes 6 (17.14%) 7 (12.28%) Smoking 0.8938 No 18 (51.43%) 29 (50.00%) Yes 17 (48.57%) 29 (50.00%) Alcohol consumption 0.1640 No 45 (73.77%) 56 (62.92%) Yes 16 (26.23%) 33 (37.08%) Cholesterol 4.15 ± 1.08 4.25 ± 1.10 0.6896 Triglyceride 1.38 ± 0.71 1.49 ± 0.99 0.7905 Low-density lipoprotein cholesterol 2.58 ± 0.96 2.48 ± 0.88 0.6999 High-density lipoprotein cholesterol 1.17 ± 0.34 1.33 ± 0.87 0.8345 BMI: body mass index; CAG: coronary angiography. 1007