ABC | Volume 114, Nº6, June 2020

Special Article One year follow-up Assessment of Patients Included in the Brazilian Registry of Acute Coronary Syndromes (ACCEPT) Pedro Gabriel Melo de Barros e Silva, 1, 2 O tavio Berwanger, 3 Elizabete Silva dos Santos, 4 Antônio Carlos Sobral Sousa, 5, 6 Margaret Assad Cavalcante, 7,8 Pedro Beraldo de Andrade, 9.1 0 F ernando Carvalho Neuenschwander, 11 Hugo Vargas Filho, 12 Jorge Ilha Guimarães, 13 Jadelson Andrade, 14 Angelo Amato Vincenzo de Paola, 15 Marcus Vinicius Bolivar Malachias, 16,1 7 Luiz Alberto Piva e Mattos, 13,18,19 Dalton Bertolim Precoma, 20, 21 F ernando Bacal, 22 Oscar Pereira Dutra 23 Hospital do Coração - Pesquisa Clínica, 1 São Paulo, SP - Brazil Hospital Samaritano Paulista – Cardiologia, 2 São Paulo, SP - Brazil Hospital Israelita Albert Einstein, 3 São Paulo, SP - Brazil Instituto Dante Pazzanese de Cardiologia, 4 São Paulo, SP - Brazil PPGCS e HU da Universidade Federal de Sergipe (UFS), 5 Aracaju, SE - Brazil Hospital São Lucas - Rede D`Or, 6 Aracaju, SE - Brazil Universidade do Oeste Paulista (Unoeste), 7 Presidente Prudente, SP - Brazil Hospital Regional de Presidente Prudente, 8 Presidente Prudente, SP - Brazil Faculdade de Medicina de Marilia, 9 Marilia, SP - Brazil Santa Casa de Marília, 10 Marília, SP - Brazil Hospital Vera Cruz, 11 Belo Horizonte, MG - Brazil Hospital São Vicente de Paulo, 12 Passo Fundo, RS - Brazil Sociedade Brasileira de Cardiologia, 13 Rio de Janeiro, RJ - Brazil Hospital da Bahia, 14 Salvador, BA - Brazil Universidade Federal de São Paulo Escola Paulista de Medicina, 15 São Paulo, SP - Brazil Faculdade de Ciências Médicas de Minas Gerais, 16 Belo Horizonte, MG - Brazil Instituto de Hipertensão Arterial - Diretoria Clínica, 17 Belo Horizonte, MG - Brazil Rede D`Or, São Paulo, 18 SP – Brazil Rede D`Or, Recife, 19 PE - Brazil Pontifícia Universidade Católica do Paraná - Escola de Medicina, 20 Curitiba, PR – Brazil Sociedade Hospitalar Angelina Caron – Cardiologia,21 Campina Grande do Sul, PR - Brazil Universidade de São Paulo Faculdade de Medicina Hospital das Clínicas Instituto do Coração, 22 São Paulo, SP - Brazil Instituto de Cardiologia – Fundação Universitária de Cardiologia do Rio Grande do Sul, 23 Porto Alegre, RS – Brazil Mailing Address: Pedro Gabriel Melo de Barros e Silva • Hospital Samaritano Paulista - R. Dr. Fausto Ferraz, 204-232. Postal Code 01333-030, Bela Vista, SP – Brazil E-mail: pgabriel@prestadores.samaritanopaulista.com.br Manuscript Received December 10, 2019, revised manuscript March 09, 2020, accepted April 08, 2020 DOI: https://doi.org/10.36660/abc.20190879 Abstract Background: There is lack of prospective data on evolution within one year of acute coronary syndromes (ACS) in a representative population of Brazilian patients. Objectives: To assess the prescription of evidence-based therapies, the incidence of severe outcomes and the predictors for these outcomes in a multicenter Brazilian registry of ACS patients. Methods: The ACCEPT is a prospective observational study, which included patients hospitalized with a diagnostic of ACS in 47 Brazilian hospitals. The patients were followed for a 1 year and data were collected on the medical prescription and the occurrence of major cardiovascular events (cardiovascular mortality, reinfarction and cerebrovascular accident - CVA). Values of p < 0.05 were considered statistically significant. Results: A total of 5,047 patients were included in this registry from August 2010 to April 2014. The diagnosis of ACS was confirmed in 4,782 patients (94.7%) and, among those, the most frequent diagnosis was ACS with ST segment elevation (35.8%). The rate of major cardiovascular events was 13.6 % within 1 year. Adherence to prescription of evidence-based therapy at admission was of 62.1%. Age, public service, acute myocardial infarction, CVA, renal failure, diabetes and quality of therapy were associated independently with the occurrence of major cardiovascular events. Conclusions: During the one-year follow-up of the ACCEPT registry, more than 10% of the patients had major cardiovascular events and this rate ranged according with the quality of therapy. Strategies must be elaborated to improve the use of evidence-based therapies to minimize the cardiovascular events among the Brazilian population. (Arq Bras Cardiol. 2020; 114(6):995-1003) 995